Institutional variation in hemotherapy for solid organ transplantation

Transfusion
C F DanielsonL J McCarthy

Abstract

Solid organ allograft recipients may require large amounts of blood components. The modification of components to make them safer for iatrogenically immunosuppressed transplant patients increases workload demands on blood banks and transfusion services. Institutions within the United States and Canada providing hemotherapy as support for transplant recipients were surveyed for their transfusion practices. Responses from 25 institutions provide the data for this report. In 1991, the mean intraoperative red cell requirements ranged from <1 unit for renal allograft recipients to 17.3 units for liver transplant recipients. The latter group also required the greatest amounts of platelets, fresh-frozen plasma, and cryoprecipitate. More than 75 percent of responding institutions provided either cytomegalovirus-seronegative or white cell-reduced cellular components to pediatric recipients of liver allografts and to both adult and pediatric recipients of heart, lung, and heart-lung allografts. The use of irradiated cellular blood components, although uncommon, was greatest in heart transplant recipients. The use of pretransplantation transfusions for immunomodulation was generally limited to patients awaiting a living-donor renal transp...Continue Reading

Citations

Aug 23, 2003·Anesthesia and Analgesia·Yves OzierUNKNOWN French Study Group on Blood Transfusion in Liver Transplantation
Aug 8, 2008·Current Opinion in Organ Transplantation·Yves Ozier, Mei-Yung Tsou
Oct 3, 2006·Current Opinion in Anaesthesiology·S D Kelley, G A Gregory
Oct 4, 2008·Best Practice & Research. Clinical Anaesthesiology·Keith E Littlewood
Jul 1, 2016·World Journal of Transplantation·Stuart ClelandStuart A McCluskey

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