Insufficiency of positive airway pressure treatment on increased mean platelet volume: a prospective controlled study in patients with obstructive sleep apnea syndrome.

Sleep & Breathing = Schlaf & Atmung
Bülent UlusoyMehmet Hakan Korkmaz

Abstract

To analyze the association between obstructive sleep apnea syndrome (OSAS) and some hematological variables such as mean platelet volume (MPV), platelet distribution width (PDW), and the impact of positive airway pressure (PAP) treatment on these parameters. The participants of the present prospective study consist of 36 OSAS patients diagnosed with polysomnography and recommended PAP treatment and 30 healthy members as the control group. Complete blood analyses were conducted to the patient group twice; before the initiation of the PAP treatment and 1 month after regular PAP use. The control group was administered a complete blood analyses only once. Patient and control group were compared in terms of various parameters such as MPV, PDW, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), white blood cell (WBC) values, and platelet counts. MPV value of the patient group was before and after PAP treatment significantly higher than the control group (respectively; Z = 2.246; p = 0.025, and Z = 2.033; p = 0.042). However, there were no statistically significant differences in the values before and after PAP treatment in the patient group (Z = 0.727; p = 0.467). In terms of platelet numbers and PDW values, no...Continue Reading

References

Jul 5, 2002·Respiration; International Review of Thoracic Diseases·Thomas GeiserMatthias Gugger
Jan 2, 2007·The European Respiratory Journal·W T McNicholasUNKNOWN Management Committee of EU COST ACTION B26
Mar 11, 2008·Thrombosis and Haemostasis·Harald F Langer, Meinrad Gawaz
Aug 21, 2009·Journal of Thrombosis and Haemostasis : JTH·S S SmythUNKNOWN 2009 Platelet Colloquium Participants
Mar 8, 2011·Sleep & Breathing = Schlaf & Atmung·Antonia BarcelóAlvar G N Agusti
Jan 17, 2013·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Ozlem Kar Kurt, Nebil Yildiz
Jul 3, 2013·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Asiye KanbayRamazan Demir
Oct 16, 2013·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Rashid NadeemRohit Loomba
Aug 16, 2014·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Sinem Nedime SökücüSedat Altın
Jul 15, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yusen ChenYanfang Chen
Oct 16, 2015·Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University·Sabri KoseogluHuseyin Dere
Apr 7, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Nurhan SariogluMehmet Kose
Jul 19, 2018·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Kostas ArchontogeorgisPaschalis Steiropoulos

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