Insufficient and Scant Endometrial Samples: Determining Clinicopathologic Outcomes and Consistency in Reporting

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
Emily A GoebelMichele M Weir

Abstract

There are no widely accepted pathologic criteria for reporting endometrial samples with limited tissue and no consensus on the clinical follow-up of patients with these samples. Our study compares clinicopathologic outcomes and determines reporting consistency for these samples. This was done in 3 parts: (1) retrospective chart review of all patients with reported insufficient or scant endometrial samples from 2010 to 2013 at our center to determine repeat sampling and final pathologic diagnosis; (2) survey of gynecologists about their practice for managing patients with these samples; (3) blind review of 99 cases of previously reported scant or insufficient samples in which 4 reviewers separately reassigned cases as scant, insufficient, or diagnostic. Agreement was determined across reviewers. For part (1): 1149 patients had insufficient (49%) or scant (51%) samples with no significant difference in repeat biopsy rate (33% vs. 31%; P=0.33). Final diagnosis of uterine malignancy was higher in patients with a previous insufficient sample than with scant (19% and 9%, respectively), but this was not statistically significant. For part (2): among gynecologists surveyed, 4 of 5 reported managing patients with insufficient or scant s...Continue Reading

References

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Jun 18, 2015·The Journal of Obstetrics and Gynaecology Research·Paphada WanijasombuttiChadakarn Phaloprakarn
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Sep 28, 2017·Journal of Lower Genital Tract Disease·Jeffrey W HastingsElaine Stickrath

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Citations

Dec 6, 2018·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Catalin TaraboantaC Blake Gilks
Dec 10, 2019·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Catalin TaraboantaC Blake Gilks
Mar 6, 2021·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Divya KriplaniNaveena Singh

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Methods Mentioned

BETA
biopsies
biopsy
hysterectomy

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