PMID: 5541231Jan 23, 1971

Insulin antagonist of pituitary origin in plasma of normal and diabetic subjects

British Medical Journal
P ZimmetH P Taft


Studies on ultrafiltrates of the plasma of normal and diabetic subjects have shown that a polypeptide of similar characteristics to the growth-hormone-derived polypeptide In-G is present in higher concentrations in diabetic subjects, thus indicating a possible role in the pathogenesis of diabetes mellitus. The polypeptide is absent from the plasma of hypophysectomized diabetic patients.

Related Concepts

Pathogenic Aspects
Insulin Antagonists
Pituitary Diseases
Pituitary Hormonal Agents
Diabetes, Autoimmune
Pituitary hormone preparation
Pituitary Gland
Diabetes Mellitus
Pituitary Hormone Suppressant

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