Insulin injection sites: morphology and immunohistochemistry

Forensic Science International : Synergy
R LutzR Mattern

Abstract

In a case of insulin suicide in a nondiabetic woman, insulin was detected in routinely formalin fixed and paraffin embedded subcutaneous injection marks, in spite of a post-morterm interval of 24 days. Around birefringent crystalline material, probably zinc phosphate, immunohistochemistry revealed granular insulin depots as well as an insulin staining along the lipocyte membranes. A cellular reaction of granulocytic character was present, with an uptake of insulin by inflammatory cells.

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Citations

May 19, 1998·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·I SuemitsuT Ohya
Jul 7, 2000·Forensic Science International : Synergy·F WehnerJ Subke
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Jun 12, 2013·Diabetes Research and Clinical Practice·Vincent Marks, Gwen Wark
Sep 16, 2000·The American Journal of Forensic Medicine and Pathology·D C Winston
May 2, 2021·International Journal of Legal Medicine·Charline BottinelliJérôme Guitton

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