PMID: 3319972Oct 1, 1987Paper

Insulin receptor evaluation in congenital generalized lipodystrophy. Case report of an infant

Helvetica paediatrica acta
M AricòP Fratino

Abstract

Insulin specific receptors on red blood cells and cultured fibroblasts were investigated in a male infant affected of congenital generalized lipodystrophy (CGL). Total insulin binding capacity appeared mildly reduced, with apparently selective involvement of the high-affinity receptors on red blood cells but not on fibroblasts. Such alterations did not produce any impairment of glucose metabolism.

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