PMID: 18406246Apr 15, 2008Paper

Insulin resistance in prepubertal African-American and Hispanic girls with premature adrenarche: a risk factor for polycystic ovary syndrome

Trends in Endocrinology and Metabolism : TEM
J DiMartino-Nardi

Abstract

Recently, the modest hyperandrogenism of premature adrenarche has been linked to the more severe hyperandrogenism of polycystic ovary syndrome (PCOS). The presence of hyperandrogenism, obesity, acanthosis nigricans, hyperinsulinism and reduced insulin sensitivity in girls with premature adrenarche and in women with PCOS suggests that the two conditions might have a common mechanism. As the early appearance of pubic hair might be the first presentation of hyperandrogenism and insulin resistance, these girls should have continued.

References

Feb 1, 1977·The Journal of Clinical Endocrinology and Metabolism·T J McKennaG W Liddle
Dec 1, 1979·The Journal of Clinical Endocrinology and Metabolism·G C LachelinS S Yen
Sep 1, 1991·The Journal of Clinical Endocrinology and Metabolism·A DunaifL Lewy
Jan 1, 1990·The Journal of Clinical Endocrinology and Metabolism·S E OberfieldL S Levine
Jun 1, 1990·The Journal of Clinical Endocrinology and Metabolism·W S CutfieldM A Sperling
Mar 1, 1990·Diabetes/metabolism Reviews·M I Harris
Oct 1, 1989·The Journal of Clinical Endocrinology and Metabolism·A H MorrisD M Mayes
Nov 1, 1989·American Journal of Obstetrics and Gynecology·J E NestlerW G Blackard
Mar 1, 1987·The Journal of Clinical Endocrinology and Metabolism·J W TemeckM I New
Jan 1, 1985·Endocrine Reviews·R N BergmanM Ader
Sep 1, 1983·Acta paediatrica Scandinavica·R VoutilainenD Apter
Jun 1, 1981·The Journal of Clinical Endocrinology and Metabolism·B H RichP Otto
Aug 1, 1981·The Journal of Clinical Endocrinology and Metabolism·R A Lobo, U Goebelsmann
Feb 1, 1995·The Journal of Clinical Endocrinology and Metabolism·E OppenheimerJ DiMartino-Nardi
Jul 1, 1994·Journal of the American Academy of Dermatology·R A Schwartz

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Citations

May 31, 2012·International Journal of Pediatric Endocrinology·Nouhad RaissouniDavid Geller
Jul 9, 2004·Journal of Pediatric Endocrinology & Metabolism : JPEM·Solange Garcia AccettaPoli Mara Spritzer
Aug 22, 2018·Pediatrics International : Official Journal of the Japan Pediatric Society·Onur AkınPeyami Cinaz
Apr 16, 2019·Pediatric Annals·Leah Khan

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