Insulin therapy in children and adolescents

Endocrinology and Metabolism Clinics of North America
William V Tamborlane, Kristin A Sikes

Abstract

Insulin therapy is the mainstay of treatment in children and adolescents with type 1 diabetes (T1D) and is a key component in the treatment of type 2 diabetes (T2D) in this population as well. A major aim of current insulin replacement therapy is to simulate the normal pattern of insulin secretion as closely as possible. This aim can best be achieved with basal-bolus therapy using multiple daily injections (MDI) or continuous insulin infusion (CSII) pump therapy. Only a few years ago, options for insulin formulations were limited. There are now more than 10 varieties of biosynthetic human and analogue insulin.

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Citations

Sep 27, 2012·Diabetes Technology & Therapeutics·Jaime RealsenH Peter Chase
Oct 12, 2013·Indian Journal of Pediatrics·Vandana Jain
Dec 23, 2014·Diabetes/metabolism Research and Reviews·Eyal J ScheinmanDerek LeRoith
Jul 31, 2013·Arquivos brasileiros de endocrinologia e metabologia·Barbara PicciniMaurizio de Martino
Jan 25, 2018·Nutrients·Giorgia TasciniSusanna Esposito

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