Integrated assessment of ceria nanoparticle impacts on the freshwater bivalve Dreissena polymorpha

Nanotoxicology
Maël GaraudLaure Giamberini

Abstract

Exposures in realistic environmental conditions are essential to properly assess the effects of emerging pollutants on ecosystems. While ceria nanoparticles (nCeO2) production and use are expanding quickly, ecotoxicity studies remain very scarce. In this study, we set up experimental systems reproducing a simplified ecosystem to assess the effects of a chronic exposure to citrate-coated nCeO2 (ci-CeO2) and bare nCeO2 (ba-CeO2) on the freshwater mussel Dreissena polymorpha using an integrated multibiomarker approach. The fate of nanoparticles was tightly monitored to properly characterize the exposure. Organisms were exposed for 3 weeks and sampled weekly for biomarker analysis. Mussel filter-feeding activity resulted in significant removal of nCeO2 from the water column. At the same time, bioaccumulation was low, reaching its maximum in the first week. Mussels bioaccumulated ci-CeO2 three times more than ba-CeO2, probably due to coating-related differences in their behavior in the water column and in organisms. Meanwhile, biomarker results were integrated and synthesized using linear discriminant analysis, highlighting that pi-glutathione-S-transferase (piGST) mRNA, catalase (CAT) activity and lysosomal system were the most imp...Continue Reading

References

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Citations

Jun 23, 2016·The Science of the Total Environment·Kahina MehennaouiArno C Gutleb
Jun 19, 2017·Environmental Science and Pollution Research International·Florence Maunoury-DangerMichael Danger
Mar 30, 2019·Environmental Science and Pollution Research International·Vanessa Koehlé-DivoBénédicte Sohm
Jul 2, 2019·Ecotoxicology and Environmental Safety·M ParantC Cossu-Leguille
Feb 15, 2021·The Science of the Total Environment·Camilla Della TorreAndrea Binelli
Jan 8, 2021·Environmental Science and Pollution Research International·Mohamed DellaliFehmi Boufahja

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