Integrated risk mapping and landscape characterisation of lymphatic filariasis and loiasis in South West Nigeria

Parasite Epidemiology and Control
Tara A BrantLouise A Kelly-Hope

Abstract

Nigeria has the heaviest burden of lymphatic filariasis (LF) in sub-Saharan Africa, which is caused by the parasite Wuchereria bancrofti and transmitted by Anopheles mosquitoes. LF is targeted for elimination and the national programme is scaling up mass drug administration (MDA) across the country to interrupt transmission. However, in some regions the co-endemicity of the filarial parasite Loa loa (loiasis) is an impediment due to the risk of severe adverse events (SAEs) associated with the drug ivermectin. To better understand factors influencing LF elimination in loiasis areas, this study conducted a cross-sectional survey on the prevalence and co-distribution of the two infections, and the potential demographic, landscape, human movement, and intervention-related risk factors at a micro-level in the South West zone of Nigeria. In total, 870 participants from 10 communities on the fringe of a meso-endemic loiasis area of Osun State were selected. LF prevalence was measured by clinical assessment and using the rapid immunochromatographic test (ICT) to detect W. bancrofti antigen. Overall LF prevalence was low with ICT positivity ranging from 0 to 4.7%, with only 1 hydrocoele case identified. Males had significantly higher IC...Continue Reading

Citations

Sep 17, 2019·Parasites & Vectors·Obiora A EneanyaChristl A Donnelly
Aug 21, 2019·International Journal of Health Geographics·Marisa HastUNKNOWN Southern and Central Africa International Centers of Excellence for Malaria Research
Apr 30, 2020·Environmental Science and Pollution Research International·Amr El-Sayed, Mohamed Kamel
Sep 19, 2018·Parasites & Vectors·Obiora A EneanyaChristl A Donnelly
Apr 8, 2021·Urban Forestry & Urban Greening·Yang Ye, Hongfei Qiu

❮ Previous
Next ❯

Methods Mentioned

BETA
MDA
PCR

Software Mentioned

Geoprocessing ( Buffer )
CDTI
ArcGIS
Statistical Package for the Social Sciences ( SPSS )
Rapid Epidemiological Mapping of Onchocerciasis ( REMO )
GPELF
Spatial Analyst Tools ( Zonal Statistics )
RAPLOA
Google Earth
GlobCover

Related Concepts

Related Feeds

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.