Integrating clinical staging and phenomenological psychopathology to add depth, nuance, and utility to clinical phenotyping: a heuristic challenge.

The Lancet. Psychiatry
Barnaby NelsonAnthony V Fernandez

Abstract

Psychiatry has witnessed a new wave of approaches to clinical phenotyping and the study of psychopathology, including the US National Institute of Mental Health's Research Domain Criteria, clinical staging, network approaches, the Hierarchical Taxonomy of Psychopathology, the general psychopathology factor, and a revival of interest in phenomenological psychopathology. The question naturally emerges about what the relationship between these new approaches is. Are they mutually exclusive and competing approaches, or can they be integrated in some way and be used to enrich each other? In this Personal View, we propose a possible integration between clinical staging and phenomenological psychopathology. Domains identified in phenomenological psychopathology (eg, selfhood, embodiment, and affectivity) can be overlaid on clinical stages to enrich and deepen the phenotypes captured in clinical staging (creating high-resolution clinical phenotypes). This approach might be useful both ideographically and nomothetically, to complement diagnosis, enrich clinical formulation, inform treatment of individual patients, and help to guide aetiology research, prediction of clinical trajectory and treatment. Overlaying phenomenological domains o...Continue Reading

References

Jun 1, 1973·Psychological Reports·A Flemenbaum, R L Zimmermann
Sep 24, 2005·Psychopathology·Josef ParnasDan Zahavi
Jul 27, 2006·The Australian and New Zealand Journal of Psychiatry·Patrick D McGorryHenry J Jackson
Oct 7, 2006·Schizophrenia Bulletin·Paul E Mullen
Apr 5, 2012·The Journal of Medicine and Philosophy·Matthew Ratcliffe
Oct 2, 2012·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Julie NordgaardJosef Parnas
Oct 8, 2013·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Patrick D McGorry
Feb 4, 2014·The Medical Journal of Australia·Debra J RickwoodPatrick D McGorry
Oct 3, 2014·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Patrick McGorryIan Hickie
Nov 18, 2014·Frontiers in Psychology·Brice MartinAnne Giersch
Feb 10, 2016·Frontiers in Psychiatry·Frauke Schultze-LutterPeter J Uhlhaas
Mar 8, 2017·Psychopathology·Louis SassNev Jones
Oct 5, 2017·JAMA Psychiatry·Michele PolettiAndrea Raballo
Oct 7, 2017·Early Intervention in Psychiatry·Jessica A HartmannPatrick D McGorry
Jan 10, 2018·Frontiers in Human Neuroscience·Mariateresa SestitoVittorio Gallese
Jan 27, 2018·Schizophrenia Bulletin·Maja Zandersen, Josef Parnas
Apr 25, 2018·Frontiers in Human Neuroscience·Brice MartinAnne Giersch
Apr 26, 2018·The British Journal of Psychiatry : the Journal of Mental Science·Barnaby NelsonJosef Parnas
Jun 2, 2018·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Patrick D McGorryBarnaby Nelson
Nov 13, 2018·Philosophical Psychology·Wayne MartinGareth S Owen
Jan 3, 2019·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Barnaby NelsonThomas J Whitford
Jan 3, 2019·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Maja Zandersen, Josef Parnas
Jan 24, 2019·Early Intervention in Psychiatry·Jean AddingtonGlenda MacQueen
Nov 5, 2019·Consciousness and Cognition·B NelsonT J Whitford
Apr 24, 2020·Annals of General Psychiatry·Mario Maj
May 13, 2020·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Jai L ShahUNKNOWN International Working Group on Transdiagnostic Clinical Staging in Youth Mental Health

❮ Previous
Next ❯

Citations

Mar 22, 2021·The Lancet. Psychiatry·Andrea Raballo, Michele Poletti
Jul 7, 2021·Schizophrenia Research·Pavan S BrarMelissa A Kalarchian
Mar 31, 2021·Journal of Behavioral Addictions·Lucero MunguíaFernando Fernández-Aranda
Nov 9, 2021·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Graeme C Smith

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The British Journal of Psychiatry : the Journal of Mental Science
K Jaspers
Psychiatria Hungarica : A Magyar Pszichiátriai Társaság tudományos folyóirata
János Csorba
© 2021 Meta ULC. All rights reserved