journal cover

Integrating computational biology and forward genetics in Drosophila

PLoS Genetics

Jan 24, 2009

Stein AertsXiao-Jiang Quan

Abstract

Genetic screens are powerful methods for the discovery of gene-phenotype associations. However, a systems biology approach to genetics must leverage the massive amount of "omics" data to enhance the power and speed of functional gene discovery in vivo. Thus far, few computational method...read more

Mentioned in this Paper

Photoreceptors
Establishment and Maintenance of Localization
Biochemical Pathway
Molecular Helix
Genome
Entire Retina
Notch
RNA, Small Interfering
Cosuppression
Drosophila melanogaster Proteins
Paper Details
References
  • References49
  • Citations14
12345
  • References49
  • Citations14
12

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Integrating computational biology and forward genetics in Drosophila

PLoS Genetics

Jan 24, 2009

Stein AertsXiao-Jiang Quan

PMID: 19165344

DOI: 10.1371/journal.pgen.1000351

Abstract

Genetic screens are powerful methods for the discovery of gene-phenotype associations. However, a systems biology approach to genetics must leverage the massive amount of "omics" data to enhance the power and speed of functional gene discovery in vivo. Thus far, few computational method...read more

Mentioned in this Paper

Photoreceptors
Establishment and Maintenance of Localization
Biochemical Pathway
Molecular Helix
Genome
Entire Retina
Notch
RNA, Small Interfering
Cosuppression
Drosophila melanogaster Proteins

Similar Papers Found In These Feeds

Signal Transduction & Gene Expression (Keystone)

Tumor cells have their own unique signal transduction and gene expression control. Targeting these specific cellular mechanisms and genetic proflies of cancer cells is an area of therapeutic exploration for some cancers. Discover the latest research on this topic with this feed.

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Related Papers

Nature Biotechnology

Gene prioritization through genomic data fusion

Nature BiotechnologyMay 9, 2006
Stein AertsYves Moreau
Paper Details
References
  • References49
  • Citations14
12345
  • References49
  • Citations14
12
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