Integrating Multimodal Radiation Therapy Data into i2b2

Applied Clinical Informatics
Eric ZapletalAnita Burgun

Abstract

Clinical data warehouses are now widely used to foster clinical and translational research and the Informatics for Integrating Biology and the Bedside (i2b2) platform has become a de facto standard for storing clinical data in many projects. However, to design predictive models and assist in personalized treatment planning in cancer or radiation oncology, all available patient data need to be integrated into i2b2, including radiation therapy data that are currently not addressed in many existing i2b2 sites. To use radiation therapy data in projects related to rectal cancer patients, we assessed the feasibility of integrating radiation oncology data into the i2b2 platform. The Georges Pompidou European Hospital, a hospital from the Assistance Publique - Hôpitaux de Paris group, has developed an i2b2-based clinical data warehouse of various structured and unstructured clinical data for research since 2008. To store and reuse various radiation therapy data-dose details, activities scheduling, and dose-volume histogram (DVH) curves-in this repository, we first extracted raw data by using some reverse engineering techniques and a vendor's application programming interface. Then, we implemented a hybrid storage approach by combining ...Continue Reading

Citations

Oct 28, 2019·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A Burgun

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Software Mentioned

i2b2
R
mi2b2
SchemaSpy
Informatics for Integrating Biology and the Bedside ( i2b2 )
Talend Open Studio scripts
CHAR
Eclipse
VARIAN ARIA
Correlation Analysis Plugin

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