PMID: 11567876Sep 25, 2001

Integrating stress-response and cell-cycle checkpoint pathways

Trends in Cell Biology
A K Pearce, T C Humphrey

Abstract

The DNA integrity checkpoint and stress kinase (SAPK/JNK and p38) pathways function to modulate cell-cycle, apoptotic and transcriptional responses to stress. Although initially considered to function independently, recent advances indicate a number of links between the stress-response and checkpoint pathways. Here, we consider the relationship between the stress-response and checkpoint pathways and how they interact to modulate cell-cycle control.

References

Jan 11, 2005·Birth Defects Research. Part A, Clinical and Molecular Teratology·Elizabeth J GribbleElaine M Faustman
Nov 13, 2007·Journal of Molecular Neuroscience : MN·Jeffery D HainesGuillermina Almazan
Apr 16, 2005·Current Opinion in Biotechnology·Gertien J Smits, Stanley Brul
Aug 29, 2003·The Journal of Surgical Research·Tammy J WestmorelandCraig B Bennett
Dec 10, 2002·Experimental Gerontology·Eveline HütterPidder Jansen-Dürr
Jun 5, 2003·Current Biology : CB·Claudine Kraft
Jun 8, 2013·Cell Death & Disease·T ArsenijevicC Delporte
Sep 28, 2004·Nature Cell Biology·Xavier EscotéFrancesc Posas
Dec 28, 2010·Nature Chemical Biology·Hai JiangMichael T Hemann
Apr 2, 2005·Nature Reviews. Molecular Cell Biology·Martin Holcik, Nahum Sonenberg
Feb 3, 2005·Cell Research·Zheng Gang Liu
Oct 3, 2009·Journal of Speech, Language, and Hearing Research : JSLHR·J Bruce TomblinKirrie Ballard
Jul 17, 2013·The Journal of Biological Chemistry·Yutaka AmakoMark Harris
May 14, 2005·Antioxidants & Redox Signaling·Emily C Rothstein, Pamela A Lucchesi
May 5, 2006·Molecular Biology of the Cell·Vladimír ReiserAngelika Amon
Oct 28, 2011·Molecular Biology of the Cell·Venkata K KuraviFrancis C Luca
Aug 2, 2002·EMBO Reports·Eulàlia de NadalFrancesc Posas
Feb 16, 2005·The Journal of Urology·John Joseph McKnightKate E Williamson
Apr 7, 2009·Biological Reviews of the Cambridge Philosophical Society·Karin S KassahnM Julian Caley
Apr 12, 2005·Eukaryotic Cell·Andrea BimbóJianhua Liu
May 6, 2010·Annual Review of Plant Biology·Maria Cristina Suarez RodriguezJohn Mundy
Dec 29, 2011·Frontiers in Bioscience (Scholar Edition)·Elphine Telles, Edward Seto
Apr 9, 2005·International Journal of Cancer. Journal International Du Cancer·Martin A ClarkJeff M P Holly
Jun 26, 2003·Differentiation; Research in Biological Diversity·Muktadir S HossainKazuhisa Sekimizu
Jan 25, 2005·Biomaterials·Helmut SchweiklGottfried Schmalz
Nov 30, 2004·Cellular Signalling·Bevin PhilipYijie Gao
Nov 12, 2003·Biochemical Pharmacology·Jim O'PreyPaul R Harrison
Feb 9, 2006·Toxicology Letters·Eva-Maria BruggerLeane Lehmann
Dec 14, 2005·Methods : a Companion to Methods in Enzymology·Alexey Khodjakov, Conly L Rieder
Mar 4, 2003·Nature Reviews. Cancer·Yosef Shiloh
Feb 4, 2012·The Journal of General Virology·Maria LicursiKensuke Hirasawa
Jul 17, 2003·International Journal of Cancer. Journal International Du Cancer·Sanjay AwasthiYogesh C Awasthi
Sep 24, 2004·International Journal of Cancer. Journal International Du Cancer·Anamaria BrozovicBernd Kaina
Jun 22, 2005·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Toshifumi FukudaMasahide Takahashi

Citations

May 1, 1990·Cancer Genetics and Cytogenetics·M SwiftD Morrell
Oct 29, 1993·Science·J T Coyle, P Puttfarcken
Oct 11, 1994·Proceedings of the National Academy of Sciences of the United States of America·G HannigR L Erikson
Jan 1, 1997·Free Radical Biology & Medicine·M H GreenC F Arlett
Apr 1, 1997·Current Opinion in Genetics & Development·R C Allshire
May 1, 1997·Chemical Research in Toxicology·E R Stadtman, B S Berlett
Nov 18, 1997·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·G Rotman, Yosef Shiloh
Oct 6, 1997·Cellular Signalling·A PaulR Plevin
Aug 26, 1998·The Journal of Biological Chemistry·C GodonJ Labarre
Nov 12, 1998·Trends in Biochemical Sciences·P Russell
Feb 17, 1999·Proceedings of the National Academy of Sciences of the United States of America·S A Jelinsky, L D Samson
Mar 25, 1999·Genes & Development·L ChenN C Walworth
Aug 18, 1999·Proceedings of the National Academy of Sciences of the United States of America·C BarlowR L Levine
Sep 2, 1999·Current Biology : CB·S S Taylor
Sep 16, 1999·Cellular and Molecular Life Sciences : CMLS·L A Tibbles, J R Woodgett
Nov 24, 1999·The Journal of Biological Chemistry·D WattersM F Lavin
Dec 23, 1999·The Journal of Biological Chemistry·S T KimM B Kastan
Feb 5, 2000·Current Biology : CB·C M GreenN F Lowndes
Mar 8, 2000·Proceedings of the National Academy of Sciences of the United States of America·G PoelzlM E Mendelsohn
Apr 5, 2000·The Journal of Biological Chemistry·Francesc PosasJ Ariño
May 10, 2000·Current Biology : CB·T Caspari
May 29, 2000·The Journal of Biological Chemistry·O PotapovaN J Holbrook
Jun 6, 2000·Trends in Biochemical Sciences·A R Nebreda, A Porras
Jun 10, 2000·Molecular and Cellular Biology·X WangJ Han
Jun 17, 2000·Trends in Cell Biology·M J O'ConnellA M Carr
Aug 1, 2000·Mutation Research·T Humphrey
Nov 7, 2000·Current Opinion in Cell Biology·N C Walworth
Nov 18, 2000·The Journal of Biological Chemistry·K VidoJ Labarre
Dec 1, 2000·Nature·B VogelsteinA J Levine
Feb 13, 2001·Molecular Biology of the Cell·M R AlexanderM C Gustin
Feb 13, 2001·Current Opinion in Genetics & Development·Yosef Shiloh

Related Concepts

Biochemical Pathway
Apoptosis, Intrinsic Pathway
Transcription, Genetic
Yeasts
Oxidative Stress
Cell Cycle
Protein KINASE
DNA Replication
DNA Integrity Checkpoint
Genotoxic Stress

Related Feeds

Cell Checkpoints & Regulators

Cell cycle checkpoints are a series of complex checkpoint mechanisms that detect DNA abnormalities and ensure that DNA replication and repair are complete before cell division. They are primarily regulated by cyclins, cyclin-dependent kinases, and the anaphase-promoting complex/cyclosome. Here is the latest research.