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Integrating the signatures of demic expansion and archaic introgression in studies of human population genomics

Current Opinion in Genetics & Development

Dec 1, 2016

Lauren Alpert Sugden, Sohini Ramachandran

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Abstract

Human population genomic studies have repeatedly observed a decrease in heterozygosity and an increase in linkage disequilibrium with geographic distance from Africa. While multiple demographic models can generate these patterns, many studies invoke the serial founder effect model, in w...read more

Mentioned in this Paper

Hominini
Study
Dysequilibrium Syndrome
Genetic Linkage
Population Group
Genome
Metazoa
Genetics, Population
Patterns
Linkage Disequilibrium
22
45
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Integrating the signatures of demic expansion and archaic introgression in studies of human population genomics

Current Opinion in Genetics & Development

Dec 1, 2016

Lauren Alpert Sugden, Sohini Ramachandran

PMID: 27743539

DOI: 10.1016/j.gde.2016.09.007

Abstract

Human population genomic studies have repeatedly observed a decrease in heterozygosity and an increase in linkage disequilibrium with geographic distance from Africa. While multiple demographic models can generate these patterns, many studies invoke the serial founder effect model, in w...read more

Mentioned in this Paper

Hominini
Study
Dysequilibrium Syndrome
Genetic Linkage
Population Group
22
45

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  • References70
  • Citations
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