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Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis

PLoS Computational Biology

Jun 17, 2016

Rebeca Campos-SánchezKateryna D Makova

Abstract

Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still have a limited understanding of how the genomic landscape influence...read more

Mentioned in this Paper

Gene Polymorphism
Establishment and Maintenance of Localization
Genome-Wide Association Study
United States Food and Drug Administration
Short Tandem Repeat
Histone antigen
Integration, Provirus
Genome
Genes
Genomic Stability
1
50
Paper Details
References
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  • Citations6
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  • References78
  • Citations6
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Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis

PLoS Computational Biology

Jun 17, 2016

Rebeca Campos-SánchezKateryna D Makova

PMID: 27309962

DOI: 10.1371/journal.pcbi.1004956

Abstract

Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still have a limited understanding of how the genomic landscape influence...read more

Mentioned in this Paper

Gene Polymorphism
Establishment and Maintenance of Localization
Genome-Wide Association Study
United States Food and Drug Administration
Short Tandem Repeat
Histone antigen
Integration, Provirus
Genome
Genes
Genomic Stability
1
50

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Parasite evolution

Parasite evolution involves the heritable genetic changes that a parasite accumulates during its life time. Discover the latest research on parasite evolution here.

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Histone modifications, including acetylation, phosphorylation, and methylation, play important roles in regulating chromatin structure and nuclear processes. They can also be passed to daughter cells as epigenetic marks. Here is the latest research on histone modification.

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Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Is there a role for endogenous retroviruses to mediate long-term adaptive phenotypic response upon environmental inputs?

Philosophical Transactions of the Royal Society of London. Series B, Biological SciencesNovember 21, 2012
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Genomic landscape of human, bat, and ex vivo DNA transposon integrations

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Paper Details
References
  • References78
  • Citations6
12345...
  • References78
  • Citations6
1
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