Integration of experiments across diverse environments identifies the genetic determinants of variation in Sorghum bicolor seed element composition

BioRxiv : the Preprint Server for Biology
Nadia ShakoorIvan Baxter


One sentence summary High-throughput measurements of element accumulation and genomewide association analysis across multiple environments identified novel alleles controlling seed mineral accumulation in Sorghum bicolor . Abstract Seedling establishment and seed nutritional quality require the sequestration of sufficient mineral nutrients. Identification of genes and alleles that modify element content in the grains of cereals, including Sorghum bicolor , is fundamental to developing breeding and selection methods aimed at increasing bioavailable mineral content and improving crop growth. We have developed a high throughput workflow for the simultaneous measurement of multiple elements in Sorghum seeds. We measured seed element levels in the genotyped Sorghum Association Panel (SAP), representing all major cultivated sorghum races from diverse geographic and climatic regions, and mapped alleles contributing to seed element variation across three environments by genome-wide association. We observed significant phenotypic and genetic correlation between several elements across multiple years and diverse environments. The power of combining high-precision measurements with genome wide association was demonstrated by implementing...Continue Reading

Related Concepts


Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.