journal cover

Integrative single-cell and bulk RNA-seq analysis in human retina identified cell type-specific composition and gene expression changes for age-related macular degeneration

bioRxiv

Sep 14, 2019

Yafei LyuMing-Yao Li

Get paper from

Abstract

Age-related macular degeneration (AMD) preferentially affects distinct cell types and topographic regions in retina. To characterize the impact of AMD on gene expression changes across retinal cell types and regions, we generated both single-cell RNA-seq (scRNA-seq) and bulk RNA-seq dat...read more

Mentioned in this Paper

Gene Expression
Neuroglia
Age Related Macular Degeneration
Macular
RNA
Methyldopa
Microglia
Genes
RNA, Small Cytoplasmic
Donor Person
64
12
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Glial Cell Differentiation

Glial cells play an essential role in maintaining brain homeostasis, forming myelin, and providing support and protection for neurons. Follow new research into glia cell differentiation with this feed.

Retinal Development: Genetics

This feed focuses on genetic, epigenetic, and transcriptomic processes pertaining to retinal development and aging.

Retinal Development And Aging: Genetics

This feed focuses on genetic, epigenetic, and transcriptomic processes pertaining to retinal development and aging. Here is the latest research.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.

Microglia And CNS Diseases

Microglia are resident macrophages of the CNS. They play a role in scavenging the CNS for plaques, phagocytosis, and extracellular signaling. Here is the latest research on their role in CNS diseases.

© 2019 Meta ULC. All rights reserved

Integrative single-cell and bulk RNA-seq analysis in human retina identified cell type-specific composition and gene expression changes for age-related macular degeneration

bioRxiv

Sep 14, 2019

Yafei LyuMing-Yao Li

DOI: 10.1101/768143

Abstract

Age-related macular degeneration (AMD) preferentially affects distinct cell types and topographic regions in retina. To characterize the impact of AMD on gene expression changes across retinal cell types and regions, we generated both single-cell RNA-seq (scRNA-seq) and bulk RNA-seq dat...read more

Mentioned in this Paper

Gene Expression
Neuroglia
Age Related Macular Degeneration
Macular
RNA
64
12
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Get paper from

/papers/integrative-single-cell-and-bulk-rna-seq-analysis/990768143