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Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies

PLoS Genetics

Apr 1, 2016

Qiongshi LuHong-Yu Zhao

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Abstract

Extensive efforts have been made to understand genomic function through both experimental and computational approaches, yet proper annotation still remains challenging, especially in non-coding regions. In this manuscript, we introduce GenoSkyline, an unsupervised learning framework to ...read more

Mentioned in this Paper

Blood
Brain
Case-Control Studies
Coronary Arteriosclerosis
Coronary Heart Disease
DNA Transposable Elements
Genome
Genome, Human
Heart
Histocompatibility Testing
15
1
77
Paper Details
References
  • References31
  • Citations8
1234

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Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies

PLoS Genetics

Apr 1, 2016

Qiongshi LuHong-Yu Zhao

PMID: 27058395

DOI: 10.1371/journal.pgen.1005947

Abstract

Extensive efforts have been made to understand genomic function through both experimental and computational approaches, yet proper annotation still remains challenging, especially in non-coding regions. In this manuscript, we introduce GenoSkyline, an unsupervised learning framework to ...read more

Mentioned in this Paper

Blood
Brain
Case-Control Studies
Coronary Arteriosclerosis
Coronary Heart Disease
15
1
77

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References31
  • Citations8
1234

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