Feb 25, 2005

Integrons and transposons on the Salmonella enterica serovar typhimurium virulence plasmid

Antimicrobial Agents and Chemotherapy
Laura Villa, Alessandra Carattoli


A virulence plasmid was identified in a multidrug-resistant Salmonella enterica serotype Typhimurium strain carrying the spvC, rck, and pefA virulence genes and two class 1 integrons linked to the Tn21 and Tn1696 transposons. A novel trimethoprim resistance gene, designated dfrA23, was also identified within the integron region. The association of multidrug resistance and virulence determinants represents an interesting example of virulence plasmid evolution.

Mentioned in this Paper

Salmonella enterica
Drug Resistance, Multiple, Bacterial
Salmonella typhimurium LT2
resistance genes
DNA Transposons

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