Mar 19, 2020

Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India

Emerging Infectious Diseases
Shilpa NaikJyoti Mathad

Abstract

Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017-January 2018, we screened pregnant women during antenatal surveillance for symptoms of mosquitoborne diseases (fever only, fever with conjunctivitis, fever with rash, or all 3 symptoms) within the previous 15 days. Of 5,843 pregnant women screened, 52 were enrolled and tested for dengue, chikungunya, and Zika viruses by using a Trioplex real-time reverse transcription PCR. Of 49 who had complete results, 7 (14%) were dengue positive. Of these ocular pain was seen in 4 (57%) and conjunctivitis in 7 (100%). Intensified symptom screening using conjunctivitis, in addition to rash, in pregnant women with fever might improve dengue case detection and can be included in routine symptom screening during pregnancy.

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Mentioned in this Paper

Detection
Conjunctivitis
Chikungunya virus
Exanthema
Antenatal Testing and Surveillance
Fever
Zika virus (organism)
Dengue Fever
Real-Time Polymerase Chain Reaction
Diagnosis

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