Intensive Gait Training for Older Adults with Symptomatic Knee Osteoarthritis

American Journal of Physical Medicine & Rehabilitation
Neil A SegalH John Yack

Abstract

The objective of this study was to determine whether individualized gait training is more effective than usual care for reducing mobility disability and pain in individuals with symptomatic knee osteoarthritis. Adults aged 60 yrs or older with symptomatic knee osteoarthritis and mobility limitations were randomized to physical therapist-directed gait training on an instrumented treadmill, with biofeedback individualized to optimize knee movements, biweekly for 3 mos or usual care (control). Mobility disability was defined using Late Life Function and Disability Index Basic Lower Limb Function score (primary); mobility limitations, using timed 400-m walk, chair-stand, and stair-climb tests; and symptoms, using the Knee Injury/Osteoarthritis Outcome Score at baseline, as well as at 3, 6, and 12 mos. The analyses used longitudinal mixed models. There were no significant intergroup differences between the 35 gait-training (74.3% women; age, 69.7 ± 8.2 yrs) and 21 control (57.1% women; age, 68.9 ± 6.5 yrs) participants at baseline. At 3 mos, the gait-training participants had greater improvement in mobility disability (4.3 ± 1.7; P = 0.0162) and symptoms (8.6 ± 4.1; P = 0.0420). However, there were no intergroup differences detected...Continue Reading

References

Sep 1, 1994·Arthritis and Rheumatism·Y C PaiJ L Lewis
May 1, 1994·Physical Therapy·A A Guccione
Feb 1, 1997·Disability and Rehabilitation·N M FisherD R Pendergast
Jan 16, 1998·Baillière's Clinical Rheumatology·L M March, C J Bachmeier
Nov 20, 1998·Archives of Physical Medicine and Rehabilitation·H RøgindH Bliddal
Jul 3, 1999·Journal of Clinical Epidemiology·R A WashburnR A Boileau
Jan 7, 2000·The American Journal of Medicine·M C Nevitt, N Lane
Mar 23, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Stephen M HaleyJacqueline Ashba
Apr 11, 2003·Arthritis and Rheumatism·Chris A McGibbonDonna Moxley Scarborough
Jun 13, 2003·Health and Quality of Life Outcomes·Ewa M Roos, Sören Toksvig-Larsen
Dec 1, 1957·Annals of the Rheumatic Diseases·J H KELLGREN, J S LAWRENCE
Apr 7, 2004·Journal of the American Geriatrics Society·Luigi FerrucciUNKNOWN Interventions on Frailty Working Group
Nov 3, 2004·Journal of Science and Medicine in Sport·B D JacksonF M Cicuttini
Nov 6, 2004·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·David B ReubenJack M Guralnik
Dec 17, 2004·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Anthony CuocoRoger A Fielding
Dec 18, 2004·Archives of Physical Medicine and Rehabilitation·Paul L de VreedeHarald J Verhaar
Mar 26, 2005·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·Tsae-Jyy WangYueh-Er Chiou
Dec 31, 2005·Arthritis and Rheumatism·Jennifer M Hootman, Charles G Helmick
May 4, 2006·JAMA : the Journal of the American Medical Association·Anne B NewmanTamara B Harris
Sep 18, 2007·IEEE Transactions on Bio-medical Engineering·Benjamin J FreglyTerese L Chmielewski
Apr 18, 2008·Medical Engineering & Physics·Shier-Chieg HuangJaung-Geng Lin
Sep 2, 2008·Arthritis and Rheumatism·Louise MurphyJoanne M Jordan
Jul 25, 2009·PM & R : the Journal of Injury, Function, and Rehabilitation·Neil A SegalMichael Nevitt
Nov 6, 2009·Archives of Physical Medicine and Rehabilitation·Neil A SegalRobert Wallace
Oct 16, 2012·Archives of Physical Medicine and Rehabilitation·Neil A SegalH John Yack
Nov 7, 2012·Annals of Internal Medicine·Shi-Yi WangRobert L Kane
Dec 4, 2012·Arthritis Care & Research·Elena LosinaJeffrey N Katz
Mar 16, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Pete B ShullMark R Cutkosky
Aug 21, 2013·PM & R : the Journal of Injury, Function, and Rehabilitation·Neil A SegalJames C Torner

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Citations

Dec 29, 2015·Osteoarthritis and Cartilage·K L BennellR S Hinman
Aug 4, 2016·Archives of Physical Medicine and Rehabilitation·Rosie RichardsJaap Harlaar
Oct 5, 2018·Foot & Ankle International·Man HungCharles L Saltzman
Sep 5, 2018·Clinical Orthopaedics and Related Research·Man HungDarrel Brodke
Oct 5, 2018·Foot & Ankle International·Man HungCharles L Saltzman
Jan 15, 2019·American Journal of Physical Medicine & Rehabilitation·Qi ZhangFeng Li
Oct 2, 2019·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Christopher Sivell
Aug 17, 2018·Journal of Neuroengineering and Rehabilitation·Angelos KaratsidisPeter H Veltink
May 17, 2019·American Journal of Physical Medicine & Rehabilitation·Qi ZhangFeng Li
Oct 23, 2020·Arthritis Care & Research·Grace ColemanDaniel K White
Aug 7, 2018·Journal of Biomechanics·Nicole T RayJill S Higginson
Jun 3, 2021·International Journal of Environmental Research and Public Health·Tomáš VodičkaStanisław Henryk Czyż

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