PMID: 5764699Mar 1, 1969

Intensive hospital monitoring of adverse reactions to drugs

British Medical Journal
N Hurwitz, O L Wade


A total of 1,268 patients admitted to hospital wards were kept under surveillance by one observer throughout their stay in hospital. All drugs given to them and the occurrence of adverse reactions were recorded.Drug reactions were found in 10.2% of the 1,160 patients who received drug therapy. Most reactions were due to known pharmacological actions of the drugs. Though only four reactions were of life-threatening seriousness, 80% of the 129 reactions observed were of moderate severity. Digitalis preparations, bronchodilator drugs, and ampicillin had the highest reaction rates. It is suggested that larger surveys of adverse reactions in relation to drug usage would make a useful contribution to the problem.


Oct 21, 1967·Lancet·M M Reidenberg
Oct 19, 1963·British Medical Journal·W P KENNEDYJ M MURDOCH
Jan 18, 1964·British Medical Journal·R A SLEETJ M MURDOCH
Jan 1, 1964·Annals of Internal Medicine·E M SCHIMMEL
Jun 15, 1964·JAMA : the Journal of the American Medical Association·L E CluffL G Seidl
Aug 1, 1965·American Journal of Public Health and the Nation's Health·L G SeidlL E Cluff


Feb 1, 1973·The Journal of Clinical Pharmacology and New Drugs·T K GrayH J Fallon
Nov 1, 1979·Journal of Clinical Pharmacology·R Spector
Nov 1, 1979·Journal of Clinical Pharmacology·V A Portnoi
Jan 1, 1985·European Archives of Psychiatry and Neurological Sciences·R GrohmannO Wunderlich
Jan 1, 1989·Psychopharmacology·R GrohmannL G Schmidt
Jan 1, 1984·European Journal of Clinical Pharmacology·R GrohmannB Wolf
Jan 1, 1987·European Journal of Clinical Pharmacology·A J TaggartG D Johnston
Jan 1, 1981·European Journal of Clinical Pharmacology·U Bergman, B E Wiholm
Oct 4, 1974·European Journal of Clinical Pharmacology·E A SotaniemiA J Kauppila
Mar 11, 1977·European Journal of Clinical Pharmacology·A SprietP Simon
Jan 1, 1986·European Journal of Clinical Pharmacology·L G SchmidtB Müller-Oerlinghausen
Jan 1, 1988·European Journal of Clinical Pharmacology·F DavidsenK Brøsen
Jan 1, 1974·The American Journal of Digestive Diseases·R B Stewart, L E Cluff
Jan 1, 1989·Irish Journal of Medical Science·G D Johnston
Sep 28, 2010·Journal of General Internal Medicine·Takeshi MorimotoD W Bates
Oct 1, 1974·Computers and Biomedical Research, an International Journal·R Baecker
Apr 1, 1995·Critical Reviews in Oncology/hematology·D S Silberstein
Jan 1, 1995·Seminars in Roentgenology·R A Gatenby
May 1, 1985·Journal of the American College of Cardiology·E Haber
Jun 17, 1971·The New England Journal of Medicine·K L Melmon
Nov 22, 1973·The New England Journal of Medicine·T W Smith, E Haber
Jun 1, 1977·British Journal of Clinical Pharmacology·D W HoltG N Volans
Jan 1, 1979·British Journal of Clinical Pharmacology·D H Lawson
May 1, 1993·British Journal of Clinical Pharmacology·A G JohnsonJ McCallum
Jun 1, 1973·Australian and New Zealand Journal of Medicine·J E Thompson
Aug 1, 1975·Australian and New Zealand Journal of Medicine·D C GerkeT I Lee
Mar 1, 1969·British Medical Journal·N Hurwitz
Mar 1, 1969·British Medical Journal·N Hurwitz
Feb 21, 1976·British Medical Journal
Feb 19, 1977·British Medical Journal
Apr 26, 1969·British Medical Journal·H Pullen
May 10, 1969·British Medical Journal
May 19, 1973·British Medical Journal·R Mulroy
Nov 10, 1979·British Medical Journal·C R Martys
Jan 3, 1981·British Medical Journal·G Rylance
Jan 30, 1982·British Medical Journal·C F George
May 14, 1983·British Medical Journal·C F George
Aug 22, 1970·British Medical Journal
Sep 26, 1970·British Medical Journal·A H Lely, Ch van Enter
Aug 11, 1973·British Medical Journal·L E Böttiger, B Westerholm
Oct 14, 1995·BMJ : British Medical Journal·A W AsscherV B Whitmarsh
Jul 3, 2004·BMJ : British Medical Journal·M PirmohamedAlasdair M Breckenridge
Sep 1, 1985·British Heart Journal·D A Chamberlain
Sep 1, 1982·Journal of Epidemiology and Community Health·C R Martys
Dec 1, 1979·Postgraduate Medical Journal·R H Falk
Jun 1, 1981·Postgraduate Medical Journal·D A HenryB Whiting
Apr 1, 1988·Postgraduate Medical Journal·P B WeedleP A Parish
Dec 4, 2003·Quality & Safety in Health Care·R K ResarD Classen
Jan 1, 1971·The Journal of Clinical Pharmacology and New Drugs·R I Wang, L C Terry
Nov 24, 1998·Journal of Clinical Pharmacology·C TranN H Shear
Jun 1, 1969·American Journal of Public Health and the Nation's Health·C M Wylie
Mar 25, 2008·Therapeutics and Clinical Risk Management·Yvonne KohShu Chuen Li
Mar 25, 2008·Therapeutics and Clinical Risk Management·Sarah N HilmerDavid G Le Couteur
Jan 18, 2013·Journal of Pharmacology & Pharmacotherapeutics·Maulik S DoshiRam K Dikshit
Jul 6, 2014·Chinese Journal of Integrative Medicine·Xing LiaoWei Yang
Jun 3, 1998·Journal of the American Medical Informatics Association : JAMIA·A K JhaD W Bates
Aug 14, 2001·Pharmacoepidemiology and Drug Safety·A K JhaD W Bates
Nov 26, 2008·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Christian G Daughton, Ilene Sue Ruhoy
Jan 2, 2016·The International Journal of Neuropsychopharmacology·M E FriedrichSiegfried Kasper
Apr 1, 1980·Journal of Gerontological Nursing·C Fitzgerald
Mar 31, 2009·Journal of Critical Care·Senaka Rajapakse, Anoja Rajapakse
Aug 3, 2006·Journal of Clinical Pharmacy and Therapeutics·E C DaviesM Pirmohamed
Dec 20, 2008·Journal of the American Geriatrics Society·Anoja RajapakseJeremy Playfer
Feb 1, 1972·American Heart Journal·A H Lely, Ch van Enter
Sep 1, 1984·International Journal of Cardiology·J L Fleg, E G Lakatta
Jan 1, 1985·Journal of Chronic Diseases·K J CarlsonR A Johnson
Nov 6, 1976·Schweizerische medizinische Wochenschrift·J Koch-Weser
Jun 1, 1984·Journal of the American Geriatrics Society·K Steel
Feb 1, 1988·Journal of the American Geriatrics Society·L Nolan, K O'Malley
Mar 1, 1983·Journal of Clinical and Hospital Pharmacy·A M Alexander, J W Barnett
Aug 1, 1988·Journal of Clinical Pharmacy and Therapeutics·P B WeedleP A Parish
Feb 1, 1982·British Journal of Clinical Pharmacology·U BustoE M Sellers
Feb 1, 1985·The Journal of Pediatrics·M S KramerD G Leduc
Sep 16, 2015·Nanomedicine·Morteza AzhdarzadehMorteza Mahmoudi
Jul 1, 1977·Journal of the American Geriatrics Society·T KalchthalerS Lichtiger
Jul 1, 1978·Journal of the American Geriatrics Society·C Salzman, R I Shader
Jul 1, 1975·Journal of the American Geriatrics Society·S R IngmanP Blake
Jul 1, 1975·Journal of the American Geriatrics Society·J E Bernstein, F K Nelson
Dec 1, 1993·Journal of the American Geriatrics Society·M B GeretyM Eimer
Jan 1, 1978·International Journal of Health Services : Planning, Administration, Evaluation
Jan 1, 1974·International Journal of Health Services : Planning, Administration, Evaluation·O L Wade, L Beeley
Apr 1, 1990·Journal of Clinical Pharmacy and Therapeutics·C A Haffner, A Main
Jun 4, 1992·The American Journal of Cardiology·R A Kelly, T W Smith
Oct 30, 1971·Lancet·D C Evered
Oct 30, 1971·Lancet·C B Adams
Nov 1, 1985·Human Toxicology·N Z Mikhael, S Kacew
Apr 1, 1984·Human Toxicology·N Z Mikhael, S Kacew
Dec 11, 1985·Drug Information Journal·R GrohmannO Wunderlich
Jun 6, 1981·British Medical Journal
Nov 1, 1977·Acta paediatrica Scandinavica·J Whyte, E Greenan
Feb 1, 1986·Journal of Clinical and Hospital Pharmacy·M Chellingsworth
Aug 25, 2019·European Archives of Psychiatry and Clinical Neuroscience·Katrin DruschkySusanne Stübner
Feb 1, 1981·JPMA. the Journal of the Pakistan Medical Association·S J Zuberi
Sep 8, 2020·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Katrin DruschkyDetlef Degner
Oct 1, 1975·British Journal of Clinical Pharmacology·D E Tesh, L Beeley
May 1, 1990·DICP : the Annals of Pharmacotherapy·P B WeedleP A Parish
Jan 12, 1978·Drug Intelligence & Clinical Pharmacy·W AdachiR C Boehm
Jun 26, 1999·British Journal of Clinical Pharmacology·G M HawksworthH Chrystyn
Dec 19, 2014·The International Journal of Neuropsychopharmacology·Christoph Josef SpindeleggerSiegfried Kasper
Oct 1, 1985·Journal of Clinical Pharmacology·J T Bigger
Aug 1, 1972·Postgraduate Medicine·G N Aagaard
Sep 1, 1976·Die Naturwissenschaften·K H Kimbel
Jan 1, 1981·British Journal of Clinical Pharmacology·M S Kramer
Jan 1, 1969·Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry·P Juul
Jun 1, 1985·Drug Intelligence & Clinical Pharmacy·S G JueM A Araki
Sep 8, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·Katrin DruschkySermin Toto
Jan 1, 1986·The British Journal of Psychiatry : the Journal of Mental Science·L G SchmidtP S Schönhöfer
Jan 1, 1969·Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry·M M Airaksinen
Jul 11, 1998·Cadernos de saúde pública·S Rozenfeld
May 1, 1983·Drug Intelligence & Clinical Pharmacy·X MasG Arbonés
Feb 1, 1971·The British Journal of Psychiatry : the Journal of Mental Science·A Q Gardiner, D J Hall
Jul 1, 1993·The Annals of Pharmacotherapy·T R Einarson
Jun 1, 1985·Journal of the American Geriatrics Society·F Budden
Jul 1, 1984·Acta Psychiatrica Scandinavica·L G SchmidtB Wolf
Apr 17, 1982·The Medical Journal of Australia·P Y Popplewell, P J Henschke

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