Intensive intracorneal keloid formation in a case of Peters plus syndrome and in Peters anomaly with maximum manifestation

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
P EberweinC Auw-Haedrich

Abstract

We present two cases of Peters anomaly (Peters plus syndrome and a maximum manifestation variant) with abnormally thickened cornea and corneal staphyloma. Both patients presented to our hospital shortly after birth and were treated with perforating keratoplasty and lensectomy. Histological analysis showed marked thickening of the corneal stroma due to abnormal stromal connective tissue deposition. Additionally, both eyes showed the characteristic changes of Peters anomaly with corneal opacity, adherence of the iris stroma and anterior lens surface to the posterior corneal surface, absence of the corneal endothelium, Descemet and Bowmans layers. Peters anomaly with abnormally thick intracorneal fibrosis with or without congenital corneal staphyloma is a very rare manifestation.

References

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Related Concepts

Multiple Congenital Anomalies
Pseudoaphakia
Cornea
Corneal Diseases
Eye Abnormalities
Keloid
Lens, Crystalline
Microphthalmos
Postoperative Complications
Repeat Surgery

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