Intensive surveillance following curative treatment of colorectal cancer allows effective treatment of recurrence even if limited to 4 years

International Journal of Colorectal Disease
Katie AdamsSavvas Papagrigoriadis

Abstract

Current evidence suggests a survival benefit to post-operative surveillance following curative colorectal cancer resection; however, there is still no consensus on the optimal duration and form. The objective is to prospectively audit outcomes of an intensive colorectal cancer follow-up scheme for time to recurrence and survival. We used a surveillance protocol designed to incorporate regular clinical, biochemical, radiological and endoscopic measures at pre-defined intervals. The setting was a Department of Colorectal Surgery in a Tertiary Academic Centre. Follow-up was led by specially trained colorectal nurses in conjunction with surgeons. Consecutive patients who had undergone curative treatment for colorectal cancer were included in this study. Outcomes were measured in terms of overall survival and disease recurrence. There were 436 patients entered into follow-up, all treated with curative intent. Mean age 65.9 years (SD 12.9 years) and 240 male (55.0 %). Ninety-four patients (21.5 %) with stage I disease, 119 (27.3 %) stage IIa, 30 (6.9 %) stage IIb, 18 (4.1 %) stage IIIa, 78 (17.9 %) stage IIIb, 45 (10.4 %) stage IIIc and 52 (11.9 %) stage IV. Overall median survival was 37.5 months for all patients, (range 0.0-207.8 m...Continue Reading

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Oct 3, 2018·ANZ Journal of Surgery·Mifanwy M ReeceMatthew J F X Rickard
Oct 21, 2020·Asia-Pacific Journal of Clinical Oncology·Samantha A PellegrinoJustin Mc Yeung
Jan 16, 2021·International Journal of Colorectal Disease·Felix WiesmuellerChristian Krautz

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