Inter-hospital variation in use of obstetrical blood transfusion: a population-based cohort study

BJOG : an International Journal of Obstetrics and Gynaecology
J A HutcheonL Lee

Abstract

To identify the extent of hospital-to-hospital variation in use of obstetrical blood transfusion. Population-based cohort study linking provincial perinatal and blood transfusion registries. British Columbia, Canada, 2004-2015. All pregnant women delivering at or beyond 20 weeks' gestation at any British Columbia hospital. Mixed-effects regression models were used to estimate hospital-specific transfusion rates after sequentially accounting for (1) the role of random variation, (2) maternal medical and obstetrical characteristics (i.e. patient case mix) and (3) institutional and delivery factors (such as use of instrumental or caesarean delivery). Hospital-specific use of obstetrical red blood cell transfusion. Among 44 hospitals, crude institutional transfusion rates across the study period ranged from 3.7 to 23.6 per 1000, with an average of 8.3 per 1000. After adjusting for maternal characteristics, institution and delivery risk factors, a nearly three-fold difference in rates between the 10th and 90th percentile remained (5.4-14.5 per 1000). Twelve sites had rates significantly higher or lower than the provincial average. Women residing in remote areas were 2.5-fold (95% CI 1.8-3.5] more likely to receive a blood transfusio...Continue Reading

References

May 7, 2003·Transfusion Medicine Reviews·Steven KleinmanPierre Robillard
Jun 29, 2005·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Brian HuttonPaul C Hébert
May 19, 2009·European Journal of Anaesthesiology·David Cardone, Andrew A Klein
Oct 14, 2010·JAMA : the Journal of the American Medical Association·Elliott Bennett-GuerreroHoward K Song
Mar 21, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·P SagotC Quantin
Jun 20, 2012·Acta Obstetricia Et Gynecologica Scandinavica·Maija JakobssonAnna-Maija Tapper
Oct 13, 2012·BMC Pregnancy and Childbirth·Azar MehrabadiK S Joseph
Jun 8, 2013·Obstetrics and Gynecology·Andrew J DillaMark H Yazer
Jul 23, 2013·American Journal of Obstetrics and Gynecology·Michael S KramerK S Joseph
Jan 11, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·B W PrickJ J Duvekot
Sep 23, 2014·Anesthesia and Analgesia·Rachel M KacmarPaloma Toledo
May 28, 2015·BMC Pregnancy and Childbirth·Gillian FrosstLily Lee
Jan 20, 2016·Journal of Blood Transfusion·Wilhellmuss I MaukaRune N Philemon
Mar 13, 2016·Acta Obstetricia Et Gynecologica Scandinavica·Tanya A NippitaChristine L Roberts
Apr 10, 2016·Transfusion·Eleni MaysonJane B Ford
Apr 4, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Audrey A MerriamBrian T Bateman
May 10, 2018·Obstetrics and Gynecology·Daniel N PaskoUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU)

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.