Inter-rater reliability of amplitude-integrated EEG for the detection of neonatal seizures.

Early Human Development
Abhijeet RakshasbhuvankarShripada C Rao

Abstract

Amplitude-integrated electroencephalogram (aEEG) is being used increasingly for seizure detection in neonates. However, data regarding inter-rater reliability among neonatologists for the use of aEEG for the detection of neonatal seizures is lacking. Term and late-preterm infants at risk of seizures were monitored simultaneously with 24-h video-electroencephalography (vEEG) and aEEG. vEEG was interpreted by an experienced neurologist. Five neonatologists with experience in aEEG interpretation from four different neonatal units interpreted aEEG recordings independently. The Brennan and Prediger kappa coefficient and Intra-class Correlation Coefficients (ICC) were used to assess inter-rater reliability between the neonatologists. Thirty-five infants at risk of seizure with gestational age at birth 35-42 weeks were recruited for the study after informed parental consent. vEEG detected seizures in seven infants with a total of 169 individual seizure episodes. Neonatologists detected seizures in 10 to 15 infants on aEEG. The sensitivities for the detection of individual seizures by neonatologists ranged from 18% to 38%. The inter-rater reliability for detection of: individual seizure was "fair" (kappa = 0.37; 95% CI: 0.32-0.42), inf...Continue Reading

Citations

Mar 6, 2021·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Carmen Bustamante-HervásJuan Arnaez
Feb 20, 2021·Frontiers in Neurology·Regina Trollmann
May 24, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Lotte NoorlagMaeike Zijlmans

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