Interacting effects of selected trace and toxic metals on thyroid function

International Journal of Environmental Health Research
Ram B Jain, Y Sammy Choi

Abstract

Interacting effects of blood levels of manganese (Mn), selenium, cadmium (Cd), lead (Pb), and mercury, and serum levels of iron (Fe), zinc (Zn), and copper (Cu) on thyroid function in general US population were evaluated. Data from the National Health and Nutrition Examination Survey for 2011-2012 were used for this evaluation. The variables used to evaluate thyroid function were as follows: thyroid-stimulating hormone, free and total triiodothyronine (FT3, TT3), free and total thyroxine (FT4, TT4), and thyroglobulin (Tg). Levels of FT4 were positively associated with the levels of copper and negatively associated with the levels of Fe for males only. Elevated levels of Mn and Fe were associated with increased levels of FT3 for both males and females. TT4 had a positive association with the levels of Cu and a negative association with the levels of Fe for both males and females.

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Citations

Mar 8, 2020·Biological Trace Element Research·Kalsoom Bibi, Munir H Shah
Sep 12, 2017·International Journal of Environmental Health Research·Hui LiYing Gao
May 19, 2018·International Journal of Molecular Sciences·Aleksandra BuhaDavid Wallace
Mar 20, 2021·Biological Trace Element Research·Tao ZhangYahong Liu
Mar 1, 2017·General and Comparative Endocrinology·Shunsuke SuzukiKiyoshi Yamauchi
Jul 3, 2021·International Journal of Molecular Sciences·Mirjana Babić LekoTatijana Zemunik

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