PMID: 108713Mar 14, 1979

Interaction between discrimination of drug states and external stimuli

Psychopharmacology
P M DuncanM D Schechter

Abstract

Rats learned a two-choice operant response by discriminating differences between external stimuli, internal (drug-produced) stimuli, or a combination of these two types of stimuli. Separate groups of rats were used for each stimulus condition. A tactile and visual external cue was superior to the ethanol-saline cue in producing stimulus control, but the group receiving both drug and external stimulus cues performed in a manner very similar to the external cue-only group. The two stimulus sources thus did not "add" to promote more rapid or complete discrimination. After acquisition of discrimination, previously coincident drug and external stimulus states were reversed to determine which stimulus source had more behavioral control. This test for stimulus selectivity indicated that the external stimulus had essentially complete control of response choice.

References

Jul 1, 1966·Journal of the Experimental Analysis of Behavior·M R D'Amato, J Fazzaro
Aug 1, 1964·Journal of Comparative and Physiological Psychology·J M WARREN

Citations

Oct 7, 2003·Integrative Physiological and Behavioral Science : the Official Journal of the Pavlovian Society·Joseph R Troisi
Nov 1, 1989·Pharmacology, Biochemistry, and Behavior·D E McMillanG R Wenger

Related Concepts

Ethanol
Metazoa
Operant Conditioning
Cues
Discrimination (Process of Differentiation)
Rats, Laboratory

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