Interaction between EDTA and sodium hypochlorite: a nuclear magnetic resonance analysis

Journal of Endodontics
Nicola Maria GrandeFrancesco Somma

Abstract

Recent studies detected erosion of the dentinal walls following the use of EDTA as a final flush. Several authors have studied degradation of EDTA and it appears to be caused by an oxidation reaction. The objective of this paper was to verify through nuclear magnetic resonance (NMR) analysis if the oxidizing property of sodium hypochlorite inactivates EDTA. Solutions of sodium hypochlorite and EDTA were analyzed. EDTA tracing and the appearance of new signals indicative of by-products of the reaction, were studied at different time intervals with a NMR analysis. The tracings of NMR analysis confirmed that the reaction between sodium hypochlorite and EDTA lead to a very slow but progressive degradation of this compound. Mindful of the limitations of an in vitro study, the results of this study nevertheless demonstrated that a final flush with sodium hypochlorite cannot limit the chelating effects of EDTA in a clinically realistic time period.

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Citations

Mar 15, 2012·Journal of Endodontics·Giampiero Rossi-FedeleJose Antonio Poli de Figueiredo
Feb 26, 2010·Dental Materials : Official Publication of the Academy of Dental Materials·Kai ZhangJun-qi Ling
Jun 2, 2009·Journal of Endodontics·Li-sha GuFranklin R Tay
Nov 26, 2008·Journal of Endodontics·Brian J RasimickAllan S Deutsch
Mar 4, 2014·Photodiagnosis and Photodynamic Therapy·Omid H MuhammadEtienne Medioni
Sep 30, 2017·Materials·Patricia P WrightLaurence J Walsh
Aug 22, 2015·Restorative Dentistry & Endodontics·Aldo Del Carpio-PerochenaAnil Kishen
May 20, 2015·Restorative Dentistry & Endodontics·Carmen LlenaAdrian Lozano
Oct 24, 2018·Microscopy Research and Technique·Yagiz Ozbay, Ali Erdemir
Feb 12, 2020·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Yuan-Ling NgKishor Gulabivala
Mar 10, 2020·BioMed Research International·Mewan Salahalddin A AlrahmanKawa F Dizaye
Mar 3, 2020·Dental Materials Journal·Marcelo Henrick Maia MatochekPaulo Henrique Perlatti D'Alpino
Dec 10, 2020·Restorative Dentistry & Endodontics·Mohannad NassarJunji Tagami
Feb 23, 2010·Journal of Endodontics·Isabel MelloJoão Humberto Antoniazzi

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