Interaction between environmental temperature and hypoxia on central and peripheral fatigue during high-intensity dynamic knee extension

Journal of Applied Physiology
Alex LloydGeorge Havenith

Abstract

This study investigated causative factors behind the expression of different interaction types during exposure to multistressor environments. Neuromuscular fatigue rates and time to exhaustion (TTE) were investigated in active men (n = 9) exposed to three climates [5 °C, 50% relative humidity (rh); 23 °C, 50% rh; and 42 °C, 70% rh] at two inspired oxygen fractions (0.209 and 0.125 FiO2; equivalent attitude = 4,100 m). After a 40-min rest in the three climatic conditions, participants performed constant-workload (high intensity) knee extension exercise until exhaustion, with brief assessments of neuromuscular function every 110 s. Independent exposure to cold, heat, and hypoxia significantly (P < 0.01) reduced TTE from thermoneutral normoxia (reductions of 190, 405, and 505 s from 915 s, respectively). The TTE decrease was consistent with a faster rate of peripheral fatigue development (P < 0.01) compared with thermoneutral normoxia (increase of 1.6, 3.1, and 4.9%/min from 4.1%/min, respectively). Combined exposure to hypoxic-cold resulted in an even greater TTE reduction (-589 s), likely due to an increase in the rate of peripheral fatigue development (increased by 7.6%/min), but this was without significant interaction between...Continue Reading

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Citations

Aug 8, 2018·International Journal of Biometeorology·Margherita RaccugliaGeorge Havenith
Jun 21, 2019·Journal of Applied Physiology·Karleigh E BradburyRobert W Kenefick
Nov 20, 2016·European Journal of Applied Physiology·Hidenori OtaniPhillip Watson
Jan 17, 2017·Temperature : Multidisciplinary Biomedical Journal·Alex Lloyd, George Havenith
Jun 9, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Alex LloydGeorge Havenith
Mar 30, 2017·Temperature : Multidisciplinary Biomedical Journal·Ashley Paul AkermanJames David Cotter
Aug 25, 2018·Frontiers in Physiology·Marine AlhammoudChristophe Hautier
Dec 14, 2018·Frontiers in Physiology·Simon HaslingerWolfgang Schobersberger
Jul 24, 2018·Frontiers in Physiology·Vanessa H PereiraFúlvia B Manchado-Gobatto
Jun 27, 2019·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Michail E KeramidasOla Eiken
Oct 20, 2020·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Alessandro ValenzaDavide Filingeri
Mar 26, 2021·European Journal of Applied Physiology·Mevra TemelAlex B Lloyd
Aug 14, 2018·Applied Ergonomics·Margherita RaccugliaSimon Hodder
May 14, 2021·Frontiers in Sports and Active Living·Fabienne Durand, Antoine Raberin
Jul 3, 2021·International Journal of Environmental Research and Public Health·Katja TomazinBelen Feriche

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