Interaction between the CheY response regulator and the histidine-containing phosphotransfer (HPt) domain of the ArcB sensory kinase in Escherichia coli

FEBS Letters
H YakuT Mizuno

Abstract

Bacteria have devised sophisticated His-Asp phosphorelay signaling systems for eliciting a variety of adaptive responses to their environment. The histidine-containing phosphotransfer (HPt) domain, found in many signal transduction protein, functions as a mediator of the His-Asp phosphorelay. The ArcB anaerobic sensor of E. coli contains such a HPt domain, although its function is not fully understood. In this study, we provide in vivo and in vitro evidence that the HPt domain is capable of interacting with the CheY receiver, which contains a phospho-accepting aspartate residue.

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Citations

Jun 22, 1999·Chemistry & Biology·M C Pirrung
Sep 25, 2002·Journal of Bacteriology·Simona RomagnoliJudith P Armitage
Nov 14, 2007·Proceedings of the National Academy of Sciences of the United States of America·Yoko EguchiRyutaro Utsumi
Dec 9, 2000·International Journal of Medical Microbiology : IJMM·M BantscheffR Gross
May 11, 2005·Molecular Microbiology·Jeffrey A GralnickDianne K Newman
Dec 12, 2007·FEMS Microbiology Reviews·Eric PotvinRoger C Levesque
Feb 11, 2005·Journal of Biomolecular Structure & Dynamics·Debashis Mukhopadhyay, Kottayil I Varughese
Jan 10, 2002·Microbiology·Daniël T VerhammeKlaas J Hellingwerf
Apr 16, 2021·Trends in Microbiology·Robert B BourretWilliam E Goldman
Apr 21, 1999·Trends in Microbiology·A L PerraudR Gross

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