Interaction of a simian papovavirus and adenoviruses. I. Induction of adenovirus tumor antigen during abortive infection of simian cells.

Journal of Bacteriology
L A FeldmanF RAPP

Abstract

Feldman, Lawrence A. (Baylor University College of Medicine, Houston, Tex.), Janet S. Butel, and Fred Rapp. Interaction of a simian papovavirus and adenoviruses. I. Induction of adenovirus tumor antigen during abortive infection of simian cells. J. Bacteriol. 91:813-818. 1966.-Adenovirus types 2, 7, and 12 undergo an abortive growth cycle in green monkey kidney cells; they induce the formation of adenovirus tumor antigen, but synthesis of adeno capsid antigen and infectious adenovirus was observed only when cultures were concomitantly infected with a simian papovavirus (SV40). Several other viruses, including herpes simplex and measles which replicate in monkey cells, and rabbit papilloma and human wart papovaviruses which do not, failed to stimulate adenovirus replication in the monkey cells. Adenovirus tumor antigen was detected 8 to 10 hr postinfection by immunofluorescent techniques. The antigen induced by adenovirus types 2 and 7 appeared as intranuclear masses; adenovirus type 12 tumor antigen also appeared as cytoplasmic and nuclear flecks. Sera from hamsters bearing tumors induced by adenovirus type 12 cross-reacted with tumor antigens induced by types 2 and 7 but not with antigens induced by SV40.

References

Sep 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·W P Rowe
Mar 1, 1962·Virology·S STINEBAUGH, J L MELNICK
Apr 1, 1963·Proceedings of the National Academy of Sciences of the United States of America·H HANAFUSAH RUBIN
Aug 1, 1963·Proceedings of the National Academy of Sciences of the United States of America·R J HUEBNERW T LANE
Jan 1, 1964·The Journal of Pediatrics·M BENYESH-MELNICK, H S ROSENBERG
May 1, 1964·Proceedings of the Society for Experimental Biology and Medicine·A S RABSONF J PAUL
Oct 1, 1964·The Journal of Experimental Medicine·J H POPE, W P ROWE
Aug 1, 1964·Proceedings of the Society for Experimental Biology and Medicine·F RAPPJ L MELNICK
Dec 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·R J HUEBNERM J CASEY
Dec 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·F RAPPT KITAHARA
Jul 1, 1965·Journal of Bacteriology·Z Gilead, H S Ginsberg
Jul 1, 1965·Journal of Bacteriology·J L MelnickF Rapp

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Citations

Jan 1, 1969·Archiv für die gesamte Virusforschung·F Rapp, M J Guentzel
Jan 1, 1972·Archiv für die gesamte Virusforschung·S S LayneF Rapp
Jan 1, 1978·Medical Microbiology and Immunology·P Hasler, R Wigand
Jan 1, 1986·Archives of Virology·G Silverstein, W A Strohl
Dec 1, 1975·Journal of Virology·D F Klessig, C W Anderson
Aug 1, 1966·Journal of Bacteriology·J S ButelF Rapp
Dec 23, 2004·Journal of Virology·Vladimir V TernovoiDavid T Curiel
Dec 1, 1987·Microbiological Reviews·K D Cockley, F Rapp

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