Interaction of hypocapnia, hypoxia, brain blood flow, and brain electrical activity in voluntary hyperventilation in humans.

Neuroscience and Behavioral Physiology
E A Burykh

Abstract

Changes in various physiological measures in voluntary hyperventilation lasting three minutes or more in humans were studied and compared. Three-minute hyperventilation, in which the rate of external ventilation increased by an average factor of 4.5-5, produced similar phasic changes in central and brain hemodynamics. The rate of circulation, indicated by rheographic data, initially increased during hyperventilation, reaching a maximum at 1-2 min of the test; there was then a reduction, to a minimum 2-3 min after the end of the test; this was followed by a further slow increase. The rate of cerebral blood flow during all 3 min of hyperventilation remained elevated in most subjects as compared with baseline and decreased during the 5 min following the end of the test. Transcutaneous carbon dioxide tension changed differently - there was a decrease to a minimum (about 25 mmHg) by the end of the test, lasting 1 min from the end of the test, this being followed by an increase to a level of 90% of baseline at 5 min after the test. Blood oxygen saturation remained at 98-100% during the test, decreasing to about 90% 5 min after the test; this, along with the decrease in cerebral blood flow, was a factor producing brain hypoxia. In dif...Continue Reading

References

May 1, 1965·Biulleten' eksperimental'noĭ biologii i meditsiny·A N Sovetov
Sep 1, 1956·Journal of Applied Physiology·A F BRADLEYM STUPFEL
Jan 1, 1957·Pflügers Archiv : European journal of physiology·O CREUTZFELDTA VAZ-FERREIRA
Feb 1, 1961·Archives of Neurology·J F FAZEKASJ F SULLIVAN
Jan 1, 1964·The American Journal of Physiology·M REIVICH

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Citations

Jul 14, 2010·The Journal of Headache and Pain·Gianluca CoppolaJean Schoenen
Feb 13, 2016·Journal of Applied Physiology·David WangRonald R Grunstein
Mar 13, 2012·Respiratory Physiology & Neurobiology·Young Sik KimHyun Ju Choi

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