Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape

Current Opinion in Microbiology
Katja SeiderBernhard Hube

Abstract

Pathogenic yeasts, either from the environment or the normal flora, have to face phagocytic cells that constitute the first line of defence during infection. In order to evade or counteract attack by phagocytes, pathogenic yeasts have acquired a repertoire of strategies to survive, colonize and infect the host. In this review we focus on the interaction of yeasts, such as Candida, Histoplasma or Cryptococcus species, with macrophages or neutrophils. We discuss strategies used by these fungi to prevent phagocytosis or to counteract phagocytic activities. We go on to describe the strategies that permit intracellular survival within phagocytes and that may eventually lead to damage of and escape from the phagocyte.

References

Jun 1, 1993·The Journal of Experimental Medicine·L G EissenbergP H Schlesinger
Mar 7, 1998·Molecular Microbiology·J W BatanghariW E Goldman
Mar 7, 2002·Proceedings of the National Academy of Sciences of the United States of America·Stephanie C Tucker, Arturo Casadevall
Sep 18, 2002·Scandinavian Journal of Immunology·A I MedeirosL H Faccioli
Oct 8, 2004·Eukaryotic Cell·Michael C LorenzGerald R Fink
Aug 10, 2005·Eukaryotic Cell·Weihua FanJoseph Heitman
Sep 12, 2006·Eukaryotic Cell·Steven S GilesJohn R Perfect
Nov 7, 2006·Current Biology : CB·Hansong MaRobin C May
Nov 7, 2006·Current Biology : CB·Mauricio Alvarez, Arturo Casadevall
Dec 23, 2006·Microbiology·Glen E PalmerJoy E Sturtevant
Feb 8, 2007·Proteomics·Harald KuschMichael Hecker
Mar 16, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M Martínez-EsparzaJ C Argüelles
Apr 26, 2007·Proceedings of the National Academy of Sciences of the United States of America·Rupinder KaurBrendan P Cormack
Aug 21, 2007·BMC Immunology·Hansong MaRobin C May
Oct 26, 2007·The Journal of Biological Chemistry·Sophia PoltermannPeter F Zipfel
Nov 17, 2007·Cell Host & Microbe·Ifat Rubin-BejeranoGerald R Fink
Dec 15, 2007·Nature Reviews. Microbiology·Mihai G NeteaNeil A R Gow
Jul 26, 2008·Medical Mycology·Louis Y A ChaiBart-Jan Kullberg
Oct 22, 2008·Infection and Immunity·Caroline CharlierFrançoise Dromer
Nov 5, 2008·Infection and Immunity·Melanie WellingtonDamian J Krysan

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Citations

Aug 27, 2013·Current Genetics·Lotte Mathé, Patrick Van Dijck
Sep 13, 2011·Human Molecular Genetics·Michèle RamsayHimla Soodyall
Nov 7, 2012·Antimicrobial Agents and Chemotherapy·Ilka Tiemy KatoMartha Simões Ribeiro
Dec 23, 2011·Journal of Clinical Microbiology·Michael S PowelNiaz Banaei
Oct 19, 2011·International Journal of Microbiology·Mircea Radu Mihu, Joshua Daniel Nosanchuk
Dec 14, 2011·International Journal of Microbiology·Hélène Tournu, Patrick Van Dijck
Sep 7, 2013·PloS One·Christian Rodriguez RodriguesJorge Geffner
Dec 24, 2011·PLoS Pathogens·Martin B Dickman, Paul de Figueiredo
Dec 14, 2012·PLoS Pathogens·Linqi Wang, Xiaorong Lin
May 4, 2011·World Journal of Biological Chemistry·André Luis Souza Dos Santos
Jun 27, 2014·PLoS Pathogens·Damian J KrysanMelanie Wellington
Nov 26, 2013·Revista iberoamericana de micología·Marcela Briones-Martin-Del-CampoAlejandro De Las Peñas
Feb 18, 2014·Fungal Genetics and Biology : FG & B·Tibor NémethAttila Gácser
Jun 19, 2012·Future Microbiology·Mayra Cuéllar-CruzEstela Ruiz-Baca
Sep 14, 2011·Annual Review of Pathology·Ronald S FlannaganSergio Grinstein
Mar 15, 2011·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Tracy Nevitt
May 10, 2013·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A KalkanciS Kuştimur
Feb 28, 2015·Biomolecules·Alessandra da Silva DantasJanet Quinn
Nov 1, 2011·Revista iberoamericana de micología·Antonio Ernesto González-GonzálezEverardo Curiel-Quesada
Nov 10, 2015·Microbial Pathogenesis·Isela Serrano-FujarteMayra Cuéllar-Cruz
May 6, 2011·Molecular Microbiology·Lívia KmetzschMarcio L Rodrigues
Dec 21, 2012·Cellular Microbiology·Sascha Brunke, Bernhard Hube
Aug 6, 2015·Cellular Microbiology·Emily F Dixon, Rebecca A Hall
Sep 22, 2015·Frontiers in Microbiology·Sandra MotaSandra Paiva
Oct 2, 2015·Briefings in Functional Genomics·Matthew Z Anderson, Richard J Bennett
Jun 13, 2015·FEMS Yeast Research·Lydia KasperBernhard Hube
Sep 19, 2012·Journal of Microbiological Methods·Charlotte A BerkesBenjamin Paradis
Feb 21, 2013·Microbes and Infection·Daciene de Arruda GrossklausCélia Maria de Almeida Soares
Nov 16, 2014·Seminars in Immunopathology·Judith BainLars-Peter Erwig
Nov 26, 2014·Seminars in Immunopathology·Anthony PlatoGordon D Brown

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