Aug 1, 1976

Interaction of plasma membranes with influenza virus. VI. The possible role of the adenylate cyclase system

Acta Virologica
O KrizanováJ Ondrusková

Abstract

The amounts of released soluble (s) antigen of influenza A/WSN virus were increased when the virus was allowed to interact with isolated plasma membranes in a medium containing substances enhancing the level of adenosine 3',5' cyclic monophosphate (c'AMP) or activating the enzyme adenylate cyclase. By contrast, less s-antigen was released upon addition to the incubation medium of foetal calf serum or calf serum proteins which activate c'AMP phosphodiesterase and thus decrease the level of c'AMP. Changes in the amount of released s-antigen were parallelled by changes in the activities of membrane Ca-adenosine triphosphatase and creatine phosphokinase.

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Mentioned in this Paper

Structure of Calf of Leg
Adenosine
Macro-Creatine Kinase
Adenosine Triphosphatases
Phosphoric diester hydrolase
Cattle calf (organism)
Influenza
Bos taurus
Serum Proteins
Creatine Kinase Measurement

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