Interaction of radiographic contrast media with immunoglobulins

RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
K Bauer

Abstract

As a special form of contrast medium incidents, various reaction modes between iodinated contrast media and immunoglobulins are described. Theoretical explanations and typical examples are given for each of the four different possible action mechanisms. Diagnostic precautions are proposed in order to avoid unfavourable reactions especially with paraproteins. Special attention is drawn to the antigen-antibody like reaction between iodinated contrast media and IgM paraproteins. Some immunological criteria are recalled to attention, this type of reaction has to meet stringently. Only by this, misinterpretation of inevident conclusions from analogy can be prevented in future similar cases.

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