Interaction of silicone oil with various intraocular lenses. A light and scanning electron microscopy study

Klinische Monatsblätter für Augenheilkunde
B DickN Pfeiffer

Abstract

Silicone oil is increasingly used as an intravitreal tamponade in severe forms of vitreoretinal disorders, also in pseudophakic eyes. In some patients silicone oil was observed to be adherent to the intraocular implant. To investigate the interaction of silicone oil with IOL-materials and the influence of lipoproteins of the serum on this interaction we used the following in vitro experimental set-up: Sterile IOLs of different IOL-materials (e.g. PMMA, silicone, hydrogel) and surface-modifications (e.g. Pharmacia 809P and 809C, Soflex LI41U, Alcon AcrySof M60BM, Allergan SI-30NB, SI-40NB, Chiron adatomed 90D, C10 and C31UB, MemoryLens U940A, Corneal ISHEMA 66, Storz H60M) were stored in vitro together with silicone oil (1000 centistokes) with and without a fresh serum solution at 37 degrees Celsius. This combination was rotated slowly and mixed thoroughly three times a day. After 3 and 6 months and a standardized special preparation in an ultrasound bath and air treatment, the IOLs were examined by light microscopy followed by scanning electron microscopy. Silicone oil strongly adhered to holes and to the IOL surface especially in silicone and PMMA IOLs. Highly hydrophylic IOLs-like the heparin-surface-modified and hydrogel IOL...Continue Reading

Citations

Nov 21, 2000·Journal of Cataract and Refractive Surgery·H B Dick, A J Augustin
Jan 3, 2001·Journal of Cataract and Refractive Surgery·O SchwennN Pfeiffer
May 20, 1999·Journal of Cataract and Refractive Surgery·K ScharweyK W Jacobi
Nov 24, 1999·Journal of Cataract and Refractive Surgery·E E SmitW F March
Apr 24, 2001·The British Journal of Ophthalmology·E McLooneR Best
Nov 1, 2001·Journal of Cataract and Refractive Surgery·S N ArthurL Werner
Dec 27, 2006·Journal of Cataract and Refractive Surgery·Aylin YamanIsmet Durak
Aug 2, 2001·International Ophthalmology Clinics·S N ArthurD J Apple
Jul 16, 1999·Ophthalmology·C Batman, O Cekiç
Nov 18, 2004·Journal français d'ophtalmologie·M S KocaboraK Engin

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