Interaction of the protein kinase Raf-1 with 14-3-3 proteins

H FuT M Roberts


Members of a family of highly conserved proteins, termed 14-3-3 proteins, were found by several experimental approaches to associate with Raf-1, a central component of a key signal transduction pathway. Optimal complex formation required the amino-terminal regulatory domain of Raf-1. The association of 14-3-3 proteins and Raf-1 was not substantially affected by the activation state of Raf.


Sep 18, 1998·Molecular Reproduction and Development·S HaraguchiE Sato
Oct 13, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M J van HemertG P van Heusden
Sep 24, 2002·Journal of Cellular Biochemistry·David AlvarezMaria Zannis-Hadjopoulos
Dec 1, 1995·Molecular Reproduction and Development·D K Morrison
Oct 1, 1996·Journal of Molecular Evolution·W Wang, D C Shakes
Jun 17, 1998·Molecular Neurobiology·E M Skoulakis, R L Davis
Apr 12, 1996·Biochemical Pharmacology·M H Melner
Jan 15, 1996·FEMS Microbiology Letters·J Goranson, D W Frank
May 29, 2004·Biochimica Et Biophysica Acta·Andrea HuwilerJosef Pfeilschifter
Apr 16, 2003·Gynecologic Oncology·A M OzaUNKNOWN NCIC Clinical Trials Group Study (NCIC IND.116)
Jul 12, 2003·Brain Research. Developmental Brain Research·Jihui ZhangA Joseph D'Ercole
Jun 24, 1998·Brain Research. Molecular Brain Research·K NamikawaH Kiyama
Apr 18, 2001·Cellular Signalling·M Silberbach, C T Roberts
Apr 21, 1999·Current Opinion in Cell Biology·T P Garrington, G L Johnson
Oct 1, 1995·Trends in Cell Biology·D J Bowles
Mar 1, 1995·Trends in Biochemical Sciences·A Aitken
Aug 24, 2013·Nature Reviews. Molecular Cell Biology·H Christian Reinhardt, Michael B Yaffe
Apr 28, 2000·European Journal of Biochemistry·B PierratJ Heim
May 31, 2001·Clinical and Experimental Pharmacology & Physiology·S M DopheideS P Jackson
Dec 29, 2007·Proceedings of the National Academy of Sciences of the United States of America·Zenggang LiHaian Fu
Sep 13, 2011·Proceedings of the National Academy of Sciences of the United States of America·Jing ZhaoHaian Fu
Aug 15, 1995·Proceedings of the National Academy of Sciences of the United States of America·D S ConklinD Beach
Oct 24, 1995·Proceedings of the National Academy of Sciences of the United States of America·N Bonnefoy-BérardA Altman
Jul 9, 1996·Proceedings of the National Academy of Sciences of the United States of America·H G WangJ C Reed
Aug 6, 1996·Proceedings of the National Academy of Sciences of the United States of America·H R MottS L Campbell
Sep 20, 2000·The Journal of Experimental Medicine·B HoyosU Hämmerling
Aug 1, 1997·Plant Physiology·K WuR J Ferl

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