Interaction of vitamin E and exercise training on oxidative stress and antioxidant enzyme activities in rat skeletal muscles

The Journal of Nutritional Biochemistry
Chen-Kang ChangTim K Tso

Abstract

It has been shown that free radicals are increased during intensive exercise. We hypothesized that vitamin E (vit E) deficiency, which will increase oxidative stress, would augment the training-induced adaptation of antioxidant enzymes. This study investigated the interaction effect of vit E and exercise training on oxidative stress markers and activities of antioxidant enzymes in red quadriceps and white gastrocnemius of rats in a 2x2 design. Thirty-two male rats were divided into trained vit E-adequate, trained vit E-deficient, untrained vit E-adequate, and untrained vit E-deficient groups. The two trained groups swam 6 h/day, 6 days/week for 8 weeks. The two vit E-deficient groups consumed vit E-free diet for 8 weeks. Vitamin E-training interaction effect was significant on thiobarbituric acid reactive substances (TBARSs), glutathione peroxidase (GPX), and superoxide dismutase (SOD) in both muscles. The trained vit E-deficient group showed the highest TBARS and GPX activity and the lowest SOD activity in both muscles. A significant vit E effect on glutathione reductase and catalase was present in both muscles. Glutathione reductase and catalase activities were significantly lower in the two vit E-adequate groups combined tha...Continue Reading

References

Aug 23, 1976·Biochemical and Biophysical Research Communications·R A Lawrence, R F Burk
Mar 1, 1992·The Journal of Nutrition·E H WittL Packer
Mar 1, 1992·The Journal of Nutrition·G Storz, L A Tartaglia
Apr 1, 1992·Molecular and Cellular Biochemistry·C T KumarP Reddanna
Dec 1, 1991·International Journal of Sports Medicine·P MenaJ E Campillo
Jun 1, 1990·Journal of Applied Physiology·M H LaughlinR J Korthuis
Jan 1, 1989·The International Journal of Biochemistry·S SumidaF Nakadomo
Jan 1, 1984·Methods in Enzymology·L Flohé, F Otting
Jan 1, 1984·Methods in Enzymology·H Aebi
Apr 1, 1995·Mutation Research·A HartmannG Speit
Sep 1, 1994·International Journal of Sport Nutrition·L RokitzkiJ Keul
Oct 1, 1993·Medicine and Science in Sports and Exercise·D CriswellS Grinton
Jan 1, 1994·Physiological Reviews·B P Yu
Feb 1, 1993·Journal of Applied Physiology·M M KanterJ O Holloszy
Dec 1, 1995·Atherosclerosis·J L Sánchez-QuesadaJ Ordóñez-Llanos
Oct 1, 1996·Journal of Applied Physiology·Y HellstenB Sjödin
Feb 1, 1996·Journal of Applied Physiology·A H GoldfarbB T Boyer
May 1, 1997·Clinical and Experimental Pharmacology & Physiology·S Oh-ishiH Ohno
Jun 1, 1997·Free Radical Research·K OkamuraY Sugawa-Katayama
Aug 1, 1997·Medicine and Science in Sports and Exercise·D A LeafT J Barstow
Dec 31, 1997·American Journal of Respiratory and Critical Care Medicine·S Oh-ishiH Ohno
Dec 31, 1997·International Journal of Sports Medicine·P Venditti, S Di Meo
Jul 3, 1998·European Journal of Applied Physiology and Occupational Physiology·T AshtonJ R Peters
Dec 19, 1998·Cell Biochemistry and Function·S D Balakrishnan, C V Anuradha
Jul 20, 1999·Journal of Applied Physiology·J Bejma, L L Ji
Jul 23, 1999·Medicine and Science in Sports and Exercise·S K PowersC Leeuwenburgh
Dec 22, 1999·Proceedings of the Society for Experimental Biology and Medicine·L L Ji
Dec 22, 1999·The Proceedings of the Nutrition Society·M J Jackson
Jan 15, 2000·The Journal of Biological Chemistry·J AbeB C Berk
Aug 4, 2001·Pflügers Archiv : European journal of physiology·J HollanderL L Ji
Jun 25, 2002·Molecular Aspects of Medicine·Malcolm J JacksonSiân B Astley
Jan 30, 2004·Exercise and Sport Sciences Reviews·David M Pattwell, Malcolm J Jackson
Feb 7, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Masayuki ItohTakeshi Matsuoka

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Citations

Nov 24, 2012·BMC Research Notes·Mahenderan AppukuttyNagaraja Haleagrahara
Sep 10, 2011·PloS One·Magdalene K MontgomeryWilliam A Buttemer
Nov 9, 2011·Sports Medicine·Tina-Tinkara Peternelj, Jeff S Coombes
Jan 7, 2014·Cell Stress & Chaperones·Fu Qing ZhaoShi Wen Xu
Sep 21, 2010·Free Radical Biology & Medicine·Meili GaoYili Wang
Dec 25, 2015·Journal of Cardiovascular and Thoracic Research·Rafigheh GhiasiRoya Naderi
Mar 13, 2016·Environmental Toxicology and Pharmacology·Xiaoying JiMeili Gao
Dec 19, 2013·Oxidative Medicine and Cellular Longevity·Jing Jye LimNorwahidah Abdul Karim
Dec 8, 2015·The Journal of Physiology·Troy L Merry, Michael Ristow
Jan 22, 2010·Nutrition Research and Practice·Eun-Young Choi, Youn-Ok Cho
Jun 28, 2016·Experimental and Therapeutic Medicine·X I LiYuan Zhang

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