PMID: 6262172Mar 1, 1981

Interactions between autonomic nerves and endocrine cells of the gastroenteropancreatic system

Diabetologia
P H Smith, K L Madson

Abstract

Autonomic nerves and endocrine cells of both the gastrointestinal tract and the pancreatic islets participate in the control of several processes related to the digestion and metabolism of nutrients. While it was once thought that they acted separately to regulate these processes, it is now appreciated that numerous interactions exist between the functions of autonomic nerves and GEP endocrine cells. Recent studies show that autonomic signals play a role in the secretory activity of various GEP cells, thus providing a mechanism by which the central nervous system can integrate digestive and metabolic functions. It also has been shown that nerves and endocrine cells frequently share certain common peptides and/or amines. Therefore, in functional terms, it is often difficult to determine whether a specific peptide of amine should be considered a neurotransmitter or a hormone. Within the next few years, one can reasonably expect that new techniques and methods of investigation will clarify the roles of putative chemical messengers such as the peptides found within autonomic nerves and the amines found within endocrine cells. It also seems likely that future studies will demonstrate that the specific chemical messenger and the mech...Continue Reading

References

Jan 1, 1977·Acta Physiologica Scandinavica·K Uvnäs-WallenstenR Luft
Jan 1, 1979·Annual Review of Physiology·M I Grossman
Dec 1, 1979·Pathology, Research and Practice·P U Heitz
Jan 1, 1976·Cold Spring Harbor Symposia on Quantitative Biology·S L Palay, V Chan-Palay
Mar 26, 1977·Lancet·T W Schwartz, J F Rehfeld
Jan 14, 1978·Lancet·S R Bloom, J M Polak
Apr 30, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·H G Joost, A Hasselblatt
Apr 30, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·R FrancoJ B Furness
Jul 1, 1979·Clinics in Endocrinology and Metabolism·D Powell, P Skrabanek
Jul 1, 1979·Clinics in Endocrinology and Metabolism·J C Floyd
Dec 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M H GreiderR L Gingerich
Jan 1, 1979·Diabetologia·J M Feldman
May 28, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·R FrancoJ B Furness
Mar 2, 1978·Histochemistry·F SundlerO Schaffalitzky de Muckadell
Mar 1, 1978·The Journal of Clinical Investigation·T W SchwartzF Stadil
Dec 1, 1978·Acta Physiologica Scandinavica·K Uvnäs-Wallensten
Jan 1, 1976·Annual Review of Pharmacology and Toxicology·P H Smith, D Porte
Nov 1, 1977·General and Comparative Endocrinology·J FontaineN M Le Douarin
Feb 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·M BodanszkyS I Said
Dec 1, 1973·European Journal of Clinical Investigation·L OrciA E Renold
Jan 1, 1980·Neuroscience·J B Furness, M Costa
Jan 1, 1980·Diabetologia·A E BishopS R Bloom
Mar 1, 1981·Diabetologia·K Uvnäs-Wallensten
Jan 1, 1980·The Journal of Clinical Endocrinology and Metabolism·D BergerS S Fajans

Citations

Oct 1, 1993·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·U LangW Künzel
Oct 1, 1983·Journal of the Autonomic Nervous System·P H Smith, B J Davis
Jan 1, 1987·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·C J Bailey, P R Flatt
Jan 1, 1983·Acta histochemica·F AmentaF Vatrella
Oct 18, 2008·Diabetes, Obesity & Metabolism·M FreebyP Harris
May 1, 1988·Diabetes/metabolism Reviews·A I Vinik, B Mitchell
Feb 1, 1986·Clinics in Endocrinology and Metabolism·E SamolsG C Weir

Related Concepts

Amines
Autonomic Nervous System
Gastrointestinal System
Endocrine Glands
Synaptic Transmission
Neurons
Pancreas
Polypeptides

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