Interactions between macroparasites and microparasites drive infection patterns in free-ranging African buffalo

Ecology
A E JollesHan Olff

Abstract

Epidemiological studies typically focus on single-parasite systems, although most hosts harbor multiple parasite species; thus, the potential impacts of co-infection on disease dynamics are only beginning to be recognized. Interactions between macroparasites, such as gastrointestinal nematodes, and microparasites causing diseases like TB, AIDS, and malaria are particularly interesting because co-infection may favor transmission and progression of these important diseases. Here we present evidence for strong interactions between gastrointestinal worms and bovine tuberculosis (TB) in free-ranging African buffalo (Syncerus caffer). TB and worms are negatively associated at the population, among-herd, and within-herd scales, and this association is not solely the result of demographic heterogeneities in infection. Combining data from 1362 buffalo with simple mechanistic models, we find that both accelerated mortality of co-infected individuals and TB transmission heterogeneity caused by trade-offs in immunity to the two types of parasites likely contribute to observed infection patterns. This study is one of the first to examine the relevance of within-host immunological trade-offs for understanding parasite distribution patterns i...Continue Reading

References

Oct 31, 1996·Nature·A K AbbasA Sher
Feb 7, 1998·American Journal of Public Health·T LietmanS Blower
Aug 15, 1998·Critical Reviews in Immunology·P A Morel, T B Oriss
Oct 1, 1998·Parasite : Journal De La Société Française De Parasitologie·J CabaretP Jacquiet
Jan 9, 1999·Parasitology·D J ShawA P Dobson
May 13, 1999·Parasite Immunology·M RodríguezR Bojalil
May 20, 1999·Research in Veterinary Science·C G RuauxR B Atwell
Dec 13, 2000·International Journal for Parasitology·J A PatzA Y Vittor
Jan 5, 2002·Evolution; International Journal of Organic Evolution·D W ColtmanJ M Pemberton
Apr 20, 2002·Science·Maria YazdanbakhshRonald van Ree
May 29, 2002·Tropical Medicine & International Health : TM & IH·Gundel Harms, Hermann Feldmeier
Apr 25, 2003·Nature·P RohaniB T Grenfell
Apr 23, 2004·Nature·Joanne LelloPeter J Hudson
Dec 4, 2004·Nature Medicine·Robin A Weiss, Anthony J McMichael
Jan 6, 2005·The Journal of Infectious Diseases·Andrea L GrahamJudith E Allen
Jun 9, 2005·The Journal of Allergy and Clinical Immunology·Susanna Cunningham-RundlesAeri Moon
Dec 14, 2005·Veterinary Microbiology·A L MichelJ Godfroid
Aug 15, 2006·Conservation Biology : the Journal of the Society for Conservation Biology·Thomas R Gillespie, Colin A Chapman
Sep 13, 2006·Parasite Immunology·D EliasS Britton
Dec 13, 2006·Proceedings of the National Academy of Sciences of the United States of America·Joseph N S EisenbergJames Trostle

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Citations

Mar 15, 2011·Oecologia·John M RomansicAndrew R Blaustein
Oct 2, 2013·Proceedings of the National Academy of Sciences of the United States of America·Pieter T J JohnsonBryan E LaFonte
Jun 22, 2011·Integrative and Comparative Biology·Nicholas P C HorrocksB Irene Tieleman
Jul 6, 2011·Integrative and Comparative Biology·Vanessa O Ezenwa, Anna E Jolles
May 10, 2013·Biology Letters·Amy B Pedersen, Janis Antonovics
Dec 21, 2012·Journal of the Royal Society, Interface·Sandra LassSarah E Perkins
Jul 7, 2009·Transboundary and Emerging Diseases·R J FlynnJ McNair
Aug 25, 2010·BMC Infectious Diseases·Lee R GibsonSusanna K Remold
Aug 31, 2011·PLoS Computational Biology·Sourya ShresthaPejman Rohani
Aug 11, 2012·PloS One·Natalie CooperCharles L Nunn
Mar 8, 2013·PloS One·Eric W SeabloomAlison G Power
Jan 1, 2011·Infection Ecology & Epidemiology·Frédéric Bordes, Serge Morand
Jun 13, 2014·PloS One·Angel StanoevLjupco Kocarev
Jan 10, 2014·Proceedings. Biological Sciences·Sanja SelakovicHans Heesterbeek
Jun 22, 2015·Preventive Veterinary Medicine·Alison HowellDiana Williams
Aug 4, 2015·International Journal for Parasitology. Parasites and Wildlife·Carly L LynsdaleVirpi Lummaa
Mar 23, 2011·Veterinary Microbiology·Daniel J O'BrienGraham Nugent
Feb 28, 2016·Journal of Theoretical Biology·Thomas CaracoIng-Nang Wang
Sep 29, 2009·Trends in Ecology & Evolution·Pablo M Beldomenico, Michael Begon
Dec 12, 2012·Comparative Immunology, Microbiology and Infectious Diseases·M MaasV P M G Rutten
Oct 7, 2015·Trends in Parasitology·Eléonore HellardDominique Pontier
Feb 18, 2011·Molecular Ecology·Amy B Pedersen, Simon A Babayan
Aug 26, 2010·The Journal of Animal Ecology·Daniel M TompkinsSandra Telfer
Mar 3, 2015·Ecology Letters·Eric W SeabloomAlison G Power
Jul 16, 2015·Integrative Zoology·Frédéric BordesSerge Morand
Jun 2, 2015·Trends in Microbiology·Ruthie B BirgerC Jessica E Metcalf
Aug 19, 2015·Parasitology·Hamish McCALLUM
Apr 2, 2015·International Journal for Parasitology. Parasites and Wildlife·Heike LutermannNigel C Bennett
Aug 5, 2014·Veterinary Parasitology·Kimberly VanderWaalVincent Obanda
Jul 30, 2011·Veterinary Parasitology·R C A Thompson, A Smith
Jun 25, 2015·Veterinary Parasitology·Valeria C ColomboPablo M Beldomenico

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