Interactions between metabolic, reward and cognitive processes in appetite control: Implications for novel weight management therapies

Journal of Psychopharmacology
Suzanne HiggsColin T Dourish

Abstract

Traditional models of appetite control have emphasised the role of parallel homeostatic and hedonic systems, but more recently the distinction between independent homeostatic and hedonic systems has been abandoned in favour of a framework that emphasises the cross talk between the neurochemical substrates of the two systems. In addition, evidence has emerged more recently, that higher level cognitive functions such as learning, memory and attention play an important role in everyday appetite control and that homeostatic signals also play a role in cognition. Here, we review this evidence and present a comprehensive model of the control of appetite that integrates cognitive, homeostatic and reward mechanisms. We discuss the implications of this model for understanding the factors that may contribute to disordered patterns of eating and suggest opportunities for developing more effective treatment approaches for eating disorders and weight management.

References

Mar 1, 1979·The Quarterly Review of Biology·M Cabanac
Sep 1, 1975·Journal of Comparative and Physiological Psychology·J AntinG P Smith
Dec 1, 1975·Journal of Personality·C P Herman, D Mack
Sep 17, 1971·Science·M Cabanac
Dec 1, 1984·Neuropharmacology·J E Blundell
Jul 1, 1981·Physiology & Behavior·B J RollsK Sweeney
Mar 1, 1993·Behavioral and Neural Biology·T L Davidson, L E Jarrard
Jan 1, 1996·Neuroscience and Biobehavioral Reviews·K C Berridge
Jan 1, 1996·Neuroscience and Biobehavioral Reviews·M M Hetherington
Oct 10, 1996·European Journal of Pharmacology·S Higgs, S J Cooper
Aug 1, 1997·Brain Research. Molecular Brain Research·X M GuanA D Howard
Mar 14, 2000·Physiology & Behavior·C R ParkS C Woods
May 4, 2000·Journal of Personality and Social Psychology·A Ward, T Mann
Jul 25, 2000·Diabetes·J F GautierP A Tataranni
Feb 24, 2001·Nature·M NakazatoS Matsukura
May 11, 2001·Behavioral Neuroscience·K S LaBarM M Mesulam
Jul 27, 2002·Science·Lora K HeislerJoel K Elmquist
Mar 11, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Dianne P Figlewicz
Jun 5, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rafael R SchickVolker Schusdziarra
Aug 20, 2003·Nature Medicine·Matthew J DuringColin N Haile
Sep 2, 2003·NeuroImage·William D S KillgoreDeborah A Yurgelun-Todd
Sep 10, 2003·Trends in Cognitive Sciences·Clayton E. Curtis, Mark D'Esposito
Feb 2, 1962·Science·B G HOEBEL, P TEITELBAUM
Dec 11, 2003·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Paul J FletcherGuy A Higgins
Aug 4, 2004·Psychoneuroendocrinology·Christian BenedictWerner Kern
Feb 11, 2005·Cerebral Cortex·W Kyle SimmonsLawrence W Barsalou
Mar 24, 2005·Psychological Review·David J KavanaghJon May
Jun 1, 2005·Physiology & Behavior·Suzanne Higgs
Aug 9, 2005·Biological Psychiatry·Rudolf UherUlrike Schmidt
Aug 16, 2005·Nature·Glenda C HarrisGary Aston-Jones
Nov 3, 2005·Physiology & Behavior·T L DavidsonLeonard E Jarrard
Nov 19, 2005·Peptides·Susan A FarrJohn E Morley
Nov 26, 2005·The European Journal of Neuroscience·Amy J TindellJ Wayne Aldridge

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Citations

Jun 22, 2018·Current Opinion in Clinical Nutrition and Metabolic Care·Maartje S Spetter
Aug 21, 2018·Current Opinion in Clinical Nutrition and Metabolic Care·Anne RoefsAnita Jansen
Feb 13, 2018·Current Obesity Reports·Suzanne Higgs, Maartje S Spetter
Feb 16, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Catherine G Russell, Alan Russell
Jan 3, 2020·Journal of Oral Rehabilitation·Isabelle MaitreAdeline Braud
Feb 23, 2019·Cognitive, Affective & Behavioral Neuroscience·Onur AsciRuth M Krebs
May 5, 2020·The Proceedings of the Nutrition Society·Benjamin CrooksJohn T McLaughlin
Aug 26, 2018·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·P OustricG Finlayson
Mar 11, 2020·The International Journal of Behavioral Nutrition and Physical Activity·Catherine G Russell, Alan Russell
Oct 1, 2020·The British Journal of Nutrition·Aikaterini PalaschaHans C M van Trijp
Dec 22, 2020·Frontiers in Psychology·Marco La MarraRaffaella Perrella
Oct 5, 2021·Frontiers in Psychology·Eva FroehlichSoyoung Q Park
Oct 16, 2021·Cognitive, Affective & Behavioral Neuroscience·Maaike M H van SwietenSanjay G Manohar

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Methods Mentioned

BETA
pharmacotherapy
pharmacotherapies

Clinical Trials Mentioned

NCT01843075

Software Mentioned

Contrave

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