Interactions of viral pathogens on hospital admissions for pneumonia, croup and chronic obstructive pulmonary diseases: results of a multivariate time-series analysis.

Epidemiology and Infection
R E G UpshurM Mamdani

Abstract

Co-circulation of respiratory syncytial virus (RSV) and influenza has made the partitioning of morbidity and mortality from each virus difficult. Given the interaction between chronic obstructive lung disease (COPD) and pneumonia, often one can be mistaken for the other. Multivariate time-series methodology was applied to examine the impact of RSV and influenza on hospital admissions for bronchiolitis, pneumonia, and COPD. The Granger Causality Test, used to determine the causal relationship among series, showed that COPD and pneumonia are not influenced by RSV (P=0.2999 and 0.7725), but RSV does influence bronchiolitis (P=0.0001). Influenza was found to influence COPD, pneumonia, and bronchiolitis (P<0.0001). The use of multivariate time series and Granger causality applied to epidemiological data clearly illustrates the significant contribution of influenza and RSV to morbidity in the population.

References

Jan 9, 2003·JAMA : the Journal of the American Medical Association·William W ThompsonKeiji Fukuda
Sep 16, 2004·JAMA : the Journal of the American Medical Association·William W ThompsonKeiji Fukuda
Apr 29, 2005·The New England Journal of Medicine·Ann R FalseyEdward E Walsh

❮ Previous
Next ❯

Citations

Jan 26, 2007·Critical Care Medicine·Jean-Jacques Parienti, Fabrice Carrat
Aug 13, 2011·The Journal of School Health·SangWoo TakGeoffrey M Calvert
Jul 30, 2008·BMC Health Services Research·Rahim MoineddinRoss E G Upshur
Jun 1, 2013·North American Journal of Medical Sciences·Auda Fares
Jul 30, 2011·Chest·Gavin C DonaldsonJadwiga A Wedzicha
Feb 3, 2011·Risk Analysis : an Official Publication of the Society for Risk Analysis·Chung-Min LiaoSzu-Chieh Chen
Apr 23, 2010·Risk Analysis : an Official Publication of the Society for Risk Analysis·Chung-Min LiaoSzu-Chieh Chen
Jul 23, 2016·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Rhonda J RosychukBrian H Rowe
Aug 21, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Dahui YouStephania A Cormier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Thorax
Gavin C Donaldson, Jadwiga A Wedzicha
Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
Mohamed Hashem, Caroline Breese Hall
Emerging Infectious Diseases
Richard HeffernanDon Weiss
Emerging Infectious Diseases
James W BuehlerClarence J Peters
© 2022 Meta ULC. All rights reserved