Interactive Effects of Physical Fitness and Body Mass Index on the Risk of Hypertension

JAMA Internal Medicine
Casey CrumpKristina Sundquist

Abstract

High body mass index (BMI) and low physical fitness are risk factors for hypertension, but their interactive effects are unknown. Elucidation of interactions between these modifiable risk factors may help inform more effective interventions in susceptible subgroups. To determine the interactive effects of BMI and physical fitness on the risk of hypertension in a large national cohort. This cohort study included all 1,547,189 military conscripts in Sweden from January 1, 1969, through December 31, 1997 (97%-98% of all 18-year-old men nationwide each year), who were followed up through December 31, 2012 (maximum age, 62 years). Data analysis was conducted August 1 through August 15, 2015. Standardized aerobic capacity, muscular strength, and BMI measurements obtained at a military conscription examination. Hypertension identified from outpatient and inpatient diagnoses. A total of 93,035 men (6.0%) were diagnosed with hypertension in 39.7 million person-years of follow-up. High BMI and low aerobic capacity (but not muscular strength) were associated with increased risk of hypertension, independent of family history and socioeconomic factors (BMI, overweight or obese vs normal: incidence rate ratio, 2.51; 95% CI, 2.46-2.55; P < .0...Continue Reading

Citations

Jul 26, 2019·Medicine and Science in Sports and Exercise·Edwin C ChinParco M Siu
Mar 19, 2019·Journal of Hypertension·Patricio López-JaramilloUNKNOWN Latin American Society of Hypertension Consensus Expert Group
Apr 14, 2017·Journal of Strength and Conditioning Research·Joseph J KnapikRyan A Steelman
Apr 28, 2016·MMW Fortschritte der Medizin· Rb
Nov 22, 2016·International Journal of Obesity : Journal of the International Association for the Study of Obesity·C CrumpK Sundquist
Oct 13, 2017·Nature Reviews. Cardiology·Charlotte Andersson, Ramachandran S Vasan
Dec 25, 2019·European Heart Journal·Casey CrumpKristina Sundquist
Aug 22, 2018·Journal of Human Hypertension·Yutaka IgarashiSeiji Maeda
Oct 26, 2018·Hypertension·Robert M CareyUNKNOWN American Heart Association Professional/Public Education and Publications Committee of the Council on Hypertension; Council
Feb 12, 2019·Annals of Internal Medicine·Pontus HenrikssonFrancisco B Ortega
Nov 5, 2016·Eating and Weight Disorders : EWD·Alessandro Lechi
Apr 16, 2020·International Journal of Hypertension·Jia ZhangGuangliang Shan
Jun 24, 2017·American Journal of Epidemiology·Casey CrumpKristina Sundquist
Mar 1, 2019·Journal of Hypertension·Haruki MommaSteven N Blair
Sep 21, 2018·International Journal of Environmental Research and Public Health·Laura CorlinDoug Brugge
Aug 17, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Carmen L WilsonKirsten K Ness
Aug 29, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Casey CrumpKristina Sundquist
Sep 25, 2020·Journal of Affective Disorders·Kamila Landucci BonifácioMichael Maes
Nov 17, 2020·Journal of the American Heart Association·Conor-James MacDonaldMarie-Christine Boutron-Ruault
Mar 16, 2021·The Journal of Clinical Hypertension·Alireza KhajaviFarzad Hadaegh
Jun 17, 2021·BMC Sports Science, Medicine and Rehabilitation·James T LanglandAndrew P J Olson

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