PMID: 8598365Mar 1, 1996Paper

Interactive three dimensional inspection of patient setup in radiation therapy using digital portal images and computed tomography data

International Journal of Radiation Oncology, Biology, Physics
K GilhuijsM van Herk

Abstract

Presently, the majority of clinical tools to quantify deviations in patient setup during external beam radiotherapy is based on two-dimensional (2D) analysis of portal images. The purpose of this study is to develop a tool for the inspection of the patient setup in three dimensions (3D) and to validate its clinical advantage over methods based on 2D analysis in the presence of out-of-plane rotations. We developed an interactive procedure to quantify the setup deviation of the patient in 3D. The procedure is based on fast computation of digitally reconstructed radiographs (DRRs) in two beam directions and comparison of these DRRs with corresponding portal images. The potential of the tool is demonstrated on three selected cases of prostate and parotid gland treatment where conventional 2D analysis produced inconsistent results. The measurements from 3D analysis are compared with those obtained from the 2D analysis. Despite application of an immobilization cast, two investigated parotid gland setups showed rotational deviations in 3D up to 3 degrees. Two-dimensional analysis of these deviations produced inconsistent results. Analysis of the selected prostate setup in 3D showed a rotational deviation of 7 degrees around the left-r...Continue Reading

References

Dec 1, 1991·Physics in Medicine and Biology·J BijholdH Meertens
Sep 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J V Lebesque, R B Keus
Apr 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A F ThorntonM Correll
Mar 1, 1990·International Journal of Radiation Oncology, Biology, Physics·G W SherouseE L Chaney
Apr 1, 1988·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M van Herk, H Meertens
Jan 1, 1985·Medical Physics·R L Siddon
Jun 1, 1983·International Journal of Radiation Oncology, Biology, Physics·M GoiteinJ Wiles
Dec 1, 1995·International Journal of Radiation Oncology, Biology, Physics·M van HerkJ V Lebesque
Jul 1, 1995·Medical Physics·K G GilhuijsR E Vijlbrief
Oct 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·E GrusellP Jakobsson
May 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A BelJ V Lebesque
Nov 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M van HerkR E Vijlbrief
Nov 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A BelJ V Lebesque
Sep 30, 1993·International Journal of Radiation Oncology, Biology, Physics·M A HuntZ Fuks
Nov 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A BelJ V Lebesque

❮ Previous
Next ❯

Citations

Apr 11, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M Olofsen-van AchtA Visser
Mar 22, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Lennert S PloegerMarcel van Herk
May 22, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dirk VerellenGuy Storme
Jun 6, 2000·International Journal of Radiation Oncology, Biology, Physics·L PisaniJ Wong
Apr 16, 2003·International Journal of Radiation Oncology, Biology, Physics·Sébastien ClippeChristian Carrie
Jan 9, 1998·International Journal of Radiation Oncology, Biology, Physics·C D MubataD P Dearnaley
Mar 5, 1998·International Journal of Radiation Oncology, Biology, Physics·F F YinP Rubin
May 20, 1998·International Journal of Radiation Oncology, Biology, Physics·K Otto, B G Fallone
Dec 30, 1998·International Journal of Radiation Oncology, Biology, Physics·L A DawsonG Morton
Mar 22, 2000·International Journal of Radiation Oncology, Biology, Physics·P RemeijerJ V Lebesque
Nov 24, 1999·The British Journal of Radiology·J A StrykerR E Beatty
Sep 19, 2001·The British Journal of Radiology·K A Langmack
Jul 29, 2000·Critical Reviews in Diagnostic Imaging·S LavalléeI Bricault
Aug 18, 2000·Medical Physics·J G Li, L Xing
Jul 23, 2002·Journal of Applied Clinical Medical Physics·Kristy K BrockJames M Balter

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.