Interarm systolic blood pressure as a predictor of cardiovascular events in patients with chronic kidney disease

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Borja QuirogaJosé Luño

Abstract

Increased interarm systolic blood pressure difference (IASBPD) is associated with mortality and cardiovascular (CV) events both in the general population and in patients at high CV risk. The aim of the present study was to assess the value of IASBPD ≥ 10 mmHg for predicting CV events in patients with chronic kidney disease (CKD). The study sample comprised 652 patients with CKD (age 67 ± 15 years, 58.1% men). Follow-up was 19 ± 5 months. We recorded increased IASBPD and related factors and assessed the predictive value of this variable for CV events. We recorded diabetes mellitus in 136 patients (20.8%), history of CV disease in 213 (32.6%) and dyslipidaemia in 327 (50.1%). The mean glomerular filtration rate was 45.9 ± 18.9 mL/min/1.73 m(2), and the median albumin/creatinine ratio was 26(0-151) mg/g. IASBPD was ≥10 mmHg in 184 patients (28.1%). The factors associated with IASBPD ≥10 mmHg were age, systolic blood pressure levels, history of congestive heart failure, lower levels of high-density lipid cholesterol and higher use of hypertensive drugs. Fifty-eight patients (8.5%) developed a CV event during the follow-up. IASBPD ≥10 mmHg [HR, 1.802, 95%CI (1.054-3.079); P = 0.031] was an independent predictor of CV events. Increas...Continue Reading

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Citations

Jan 1, 2016·Lipids in Health and Disease·Maciej BanachAdrian Covic
Sep 8, 2009·BMC Clinical Pharmacology·Gunar StemerRosa Lemmens-Gruber
Oct 30, 2016·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Christopher E ClarkJohn L Campbell
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Nov 5, 2019·The International Journal of Artificial Organs·Sawako KatoShoichi Maruyama
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Mar 19, 2021·Blood Pressure Monitoring·Ismail Dogu KilicKadriye Kilickesmez Orta

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