Intercellular adhesiveness of H-2 identical and H-2 disparate cells

Journal of Immunogenetics
V ZelenýA Lengerová

Abstract

Using a 2 X 2 design, the collection rates of cells from radioactively labelled single-cell suspensions on cell-coated collecting surfaces were tested for a possible H-2 effect on intracellular adhesiveness. By a statistical procedure, the undesirable variability in the suspension and/or in the collecting surface could be eliminated, and the H-2 specific net effect estimated. In this way it was possible to detect (even on the background of a large non-specific variability) significant reductions of the allogeneic collection rates (i.e. between cells which differed only in their H-2 haplotypes) as compared to the syngeneic standards. It is concluded that cells of a given H-2 haplotype have preferential adhesiveness to syngeneic cells.

References

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Citations

Jan 1, 1985·Immunogenetics·K L McGuireP W Tucker
Jan 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·J GogusevG F Rabotti
Sep 1, 1981·Immunology Today·C R ParishD B Rylatt
Oct 1, 1988·Medical Hypotheses·B Daunter
Oct 1, 1983·Immunology Today·M Edidin
Sep 20, 1979·Nature·A S Curtis, P Rooney
Oct 1, 1981·Journal of Immunogenetics·A S Curtis, M D Davies

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