Intercellular junctions of rat endocardium

The Anatomical Record
P AnversaJ Wiener

Abstract

The ultrastructure of the intercellular junctions of rat endocardium has been characterized following lanthanum exposure in vitro and uranyl acetate staining en bloc. The interendothelial clefts of the endocardium run either a relatively straight or convoluted course and posses one or two loci where the plasma membranes are in close apposition or form punctate fusions. Elongate restrictions, that exhibit hexagonal arrays of subunits following lanthanum immersion (gap junctions), are also present in the intercellular endocardial clefts. The occurrence of interendothelial clefts of endocardium lacking occlusive foci can account for the permeability properties of ventricular endocardium, where the direction of diffusion of macromolecules has been attributed to pressure gradients between ventricular cavity and myocardium. The relationship of gap junctions to possible electrical phenomena within the endocardium is also discussed.

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Sep 1, 1994·Cell and Tissue Research·L J Andries, D L Brutsaert
Nov 1, 1996·Progress in Cardiovascular Diseases·D L BrutsaertS U Sys
Aug 12, 2006·Canadian Journal of Physiology and Pharmacology·Danielle JacquesChantale Provost
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May 1, 1982·Journal of Ultrastructure Research·H TurcotteM Boutet
Mar 1, 1983·Journal of Morphology·Timothy J McDonnell, John O Oberpriller

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