Interconnections between the prefrontal cortex and the premotor areas in the frontal lobe

The Journal of Comparative Neurology
M T LuP L Strick

Abstract

We examined interconnections between a portion of the prefrontal cortex and the premotor areas in the frontal lobe to provide insights into the routes by which the prefrontal cortex gains access to the primary motor cortex and the central control of movement. We placed multiple injections of one retrograde tracer in the arm area of the primary motor cortex to define the premotor areas in the frontal lobe. Then, in the same animal, we placed multiple injections of another retrograde tracer in and around the principal sulcus (Walker's area 46). This double labeling strategy enabled us to determine which premotor areas are interconnected with the prefrontal cortex. There are three major results of this study. First, we found that five of the six premotor areas in the frontal lobe are interconnected with the dorsolateral prefrontal cortex. Second, the major site for interactions between the prefrontal cortex and the premotor areas is the ventral premotor area. Third, the prefrontal cortex is interconnected with only a portion of the arm representation in three premotor areas (supplementary motor area, the caudal cingulate motor area on the ventral bank of the cingulate sulcus, and the dorsal premotor area), whereas it is interconne...Continue Reading

References

Jan 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D L Rosene, M M Mesulam
Apr 1, 1991·Brain : a Journal of Neurology·G di Pellegrino, S P Wise
Jan 1, 1988·Experimental Brain Research·K D HutchinsP L Strick
Jan 1, 1989·Brain, Behavior and Evolution·M GentilucciG Rizzolatti
Feb 24, 1987·Brain Research·A M Martino, P L Strick
Jan 1, 1988·Annual Review of Neuroscience·P S Goldman-Rakic
Feb 8, 1987·The Journal of Comparative Neurology·H Barbas, D N Pandya
Aug 8, 1987·The Journal of Comparative Neurology·B A VogtD L Rosene
Oct 1, 1986·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D L RoseneB J Davis
Jan 1, 1985·Annual Review of Neuroscience·S P Wise
Jul 1, 1985·Neuroscience·H Barbas, M M Mesulam
May 1, 1971·Journal of Neurophysiology·K Kubota, H Niki
Jul 1, 1982·Journal of Neurophysiology·P L Strick, J B Preston
Jan 1, 1982·Experimental Brain Research·J MacphersonT S Miles
Feb 1, 1982·The Journal of Physiology·B J Sessle, M Wiesendanger
Jul 1, 1982·Journal of Neurophysiology·P L Strick, J B Preston
Jan 10, 1981·The Journal of Comparative Neurology·E A Murray, J D Coulter

❮ Previous
Next ❯

Citations

Sep 28, 1998·Annals of Neurology·D EidelbergS Fahn
May 14, 2005·Experimental Brain Research·Tamami Fukushi, Toshiyuki Sawaguchi
Dec 7, 2010·Brain Structure & Function·Marzio GerbellaGiuseppe Luppino
Nov 7, 2012·Brain Structure & Function·Rick A AdamsKarl J Friston
Mar 1, 1995·Behavioural Brain Research·E J Tehovnik
Dec 14, 1995·Behavioural Brain Research·D BoussaoudS P Wise
Dec 1, 1994·Current Opinion in Neurobiology·A B Schwartz
Dec 4, 2003·Behavioural Brain Research·Etienne Coutureau, Simon Killcross
Jan 20, 2004·Journal of Chemical Neuroanatomy·Suzanne N Haber
May 3, 2005·NeuroImage·Clayton E CurtisMark D'Esposito
Sep 19, 1998·Electroencephalography and Clinical Neurophysiology·G RizzolattiM Matelli
Jan 16, 2003·Physiology & Behavior·Richard P Dum, Peter L Strick
Apr 13, 2000·Brain Research. Brain Research Reviews·E J TehovnikP H Schiller
May 3, 2003·Neuroscience Research·Shinji KakeiPeter L Strick
Jan 27, 1998·Brain Research Bulletin·R J Morecraft, G W Van Hoesen
Apr 18, 2003·Pediatric Neurology·Michael J RivkinDeborah P Waber
Jan 13, 2004·Neuron·Ranulfo RomoAntonio Zainos
Nov 8, 2002·Brain Research. Cognitive Brain Research·Ricarda I Schubotz, D Yves von Cramon
Dec 13, 2001·Current Opinion in Neurobiology·N Picard, P L Strick
Dec 1, 1996·Current Opinion in Neurobiology·S R Jackson, M Husain
Jan 28, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Holger WieseMatthias Keidel
Aug 7, 2012·Nature Neuroscience·Kyoko YoshidaMasaki Isoda
Oct 12, 2001·The European Journal of Neuroscience·E Procyk, J P Joseph
Feb 28, 2002·The European Journal of Neuroscience·M TakadaA Nambu
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Luis LemusRanulfo Romo
Jan 20, 2006·Brain : a Journal of Neurology·Nick S WardRichard S J Frackowiak
Apr 22, 2008·Cerebral Cortex·Numa DancauseRandolph J Nudo
Oct 14, 2010·Cerebral Cortex·Pascale Tremblay, Steven L Small
May 17, 2011·Cerebral Cortex·Sheng ZhangChiang-shan R Li

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.